1. Dietary Inflammatory Index in relation to Type 2 Diabetes: A Meta-Analysis
- Author
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Amir Motamedi, Mohammadreza Askari, Hadis Mozaffari, Reza Homayounfrar, Ali Nikparast, Maryam Lafzi Ghazi, Maryam Mofidi Nejad, and Shahab Alizadeh
- Subjects
Inflammation ,endocrine system ,Diabetes Mellitus, Type 2 ,Risk Factors ,Odds Ratio ,Humans ,General Medicine ,Diet - Abstract
Background and Aims. Epidemiologic studies show a strong association between chronic inflammation and type 2 diabetes (T2D). Diet may also affect the risk of T2D by modulating inflammation. This meta-analysis aimed to assess the relation of dietary inflammatory index (DII) and risk of T2D. Methods. PubMed and Scopus were systematically searched from their inception to September 2020 to identify relevant studies. Relative risks, hazard ratios, or odds ratios (OR), with their corresponding 95% confidence intervals (95% CI), were calculated and pooled using a random-effects model. Results. A total of 48 different studies, with a total sample size of 1,687,424 participants, were eligible to be included in this meta-analysis. In the overall analysis, no significant association was observed between DII and risk of T2D (OR = 1.03, 95% CI: 0.91 to 1.15), with significant evidence for heterogeneity (I2 = 96.5%, P
- Published
- 2021