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Background: Life of every human starts with infancy, childhood into adult life. During this process, childhood happen to be the most vulnerable phase associated with nutritional deficiency affecting the growth leading to morbidity and mortality. Malnutrition in pre-school children is considered most important indicator of the nutritional and health status of the country which is given top priority in National Family Health Survey- 4 (NFHS-4). Pre-school children in India have higher percentage of undernourished children and are 100th place among 119 malnourished countries in the world. The aims of the study were to assess the nutritional status of children aged 3-6 yrs in rural area attending Anganwadi centers under Rural Health Center, SRMC, Nandyal and to identify the factors associated with the nutritional status of pre-school children.Methods: Cross sectional study, area under Rural Health Center, Santhiram Medical College, A.P. Sample size for study is 161, calculated using Epi info-7 calculator. Study was carried during June 2017- July 2017 for a period of two months among 3-6 yrs children attending AWC under RHC, SRMC, Nandyal. Samples selected were based on using multistage random sampling technique. All the children were subjected to measure for body weight and their ages were recorded using Gomez classification based on weight for age. All the mothers were interviewed using pre tested questionnaire. The data compiled in excel sheet and later was analyzed using SPSS-22 version.Results: Total number of children between 3-6 yrs included in the study is 161. Female children (57.8%) outnumbered male children (42.2%) in the study. Undernourished children according to Gomez classification were falling in second degree with 77 (47.8%), followed by first degree 63 (39.1%). The age, mothers’ education and B G Prasad socio economic class-4 and class-5 with Under Nutrition were showing significant correlation showing p value less than 0.05. Conclusions: Mothers’ education and BG Prasad socio economic class is showing more influence on second degree and first degree under nutrition based on Gomez classification.

Background: As a part of pharmacovigilance program of India (PvPI) adverse drug reactions (ADRs) are cause of mortality and morbidity in patients unnoticed, which is a part of WHO program for International Drug Safety Monitoring across world. ADRs are considered to be among top 10 causes for mortality. The reason for sex difference in medication response is multi factorial with wide range of aspects like steroid hormones, organ physiology to psychology and socio-cultural factors. The aim was to study on gender related differences in adverse drug reactions in patients attending tertiary care teaching hospital at Nandyal.Methods: ADR cases were collected from multicenter health care units from tertiary care teaching hospital. ADRs were reported in ADR notification forms or yellow form, CDSCO forms are used to report ADR to Regional pharmacovigilance center. Causality assessment of the ADRs was done based on WHO-UMC causality assessment scale using modified Hartwig and Seigel scale.Results: In the 30 ADR reports collected 21 reports (70%) are of female patients and 9 reports (30%) are of male patients. According to WHO-UMC scale 20 (70%) of Adverse drug reactions were falling into PROBABLE, while 10 (30%) ADR’s are CERTAIN. In 21 females, ADR reports were due to 15(76.43%) Antibiotics, 2 (9.52%) NSAID’s, 2 (9.52%) proton pump inhibitors, 2 (9.52%) anti-convulsants. In 9 males, ADR reports were due to 5 (55.5%) Antibiotics, 2 (22.22%) NSAID’s, 2 (22.22%) anti-convulsants.Conclusions: ADRs are the common occurrences but ADR monitoring helps in prevention of morbidity and mortality in patients. The most commonly affected gender is among female patients, as they are more exposed to drugs starting their journey right from the childhood, pregnancy till their adult menopausal stage.

Background: Road traffic accidents (RTA) is considered to be among top five cause of concern in with morbidity and mortality with socioeconomic repercussions among developing countries. RTA’s are manmade disaster which involves human suffering and socioeconomic costs in terms of premature deaths, injuries, etc. The objective of study was to know the prevalence of various types of accidents, injuries and associated factors.Methods: This study is prospective observational study, was conducted at Tertiary Care Teaching Hospital, SRMC, A.P. Enrollment of patients were registered in emergency trauma care, included all types of accidents and injuries. Patients were interviewed with the pre-tested proforma. After written informed consent, victims were interviewed and attendants were interviewed where patients were unable to answer which is part of Inclusion criteria in the study. Injuries recorded were graded according to Trauma Index. Other required information was collected from medicolegal records from hospital medical records department.Results: Total of 153 cases recorded at emergency Trauma care unit, of which males are 135 (88.235%) and females 18 (11.764%). The highest percentage was falling between 20-29 years followed by 30-39, 40-49 years.3,4 According to trauma index injuries, Minor were 108 (70.588%) and Major were 45 (20.411%). Of all injuries RTA’s were 111 (72.549%), recorded as the major portion.2 The injuries were more due to Bikes 51 (45.945%), followed by pedestrians 30 (27.027%) as victims, which took place in the evening and late nights were 93 (60.784%), followed by early mornings were 42 (27.450%).Conclusions:Conclusions of study showed that males were involved more than females in RTA’s falling between 20-49 years. Most of the injuries recorded were minor followed by major injuries from Road Traffic Accidents, which occurred during evenings and late nights. Type of vehicles involved in RTA’s was two wheelers followed by pedestrians and people who travelled in share Autos.