7 results on '"Kraneveld, Aletta D."'
Search Results
2. Development and Validation of the Immune Status Questionnaire (ISQ)
- Author
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Wilod Versprille, Livia J.F., van de Loo, Aurora J.A.E., Mackus, Marlou, Arnoldy, Lizanne, Sulzer, Titia A.L., Vermeulen, Sterre A., Abdulahad, Smedra, Huls, Hendrikje, Baars, Ton, Scholey, Andrew, Kraneveld, Aletta D., Garssen, Johan, Verster, Joris C., One Health Toxicologie, dIRAS RA-1, Afd Pharmacoepi & Clinical Pharmacology, Afd Pharmacology, Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, One Health Toxicologie, dIRAS RA-1, Afd Pharmacoepi & Clinical Pharmacology, Afd Pharmacology, Pharmacology, and Pharmacoepidemiology and Clinical Pharmacology
- Subjects
Predictive validity ,Adult ,Male ,Self-Assessment ,immune functioning ,Health, Toxicology and Mutagenesis ,Health Status ,Perceived immune status ,Article ,Likert scale ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Surveys and Questionnaires ,Fitness ,medicine ,Humans ,Toxicology and Mutagenesis ,030212 general & internal medicine ,ISQ ,Depression (differential diagnoses) ,business.industry ,Questionnaire ,questionnaire ,Environmental and Occupational Health ,Neuropsychology ,Public Health, Environmental and Occupational Health ,Construct validity ,Immunity, Innate ,Immune functioning ,fitness ,Health ,Joint pain ,Scale (social sciences) ,Anxiety ,perceived immune status ,Female ,Public Health ,medicine.symptom ,business ,030217 neurology & neurosurgery ,Clinical psychology - Abstract
The self-assessment of perceived immune status is important, as this subjective observation leads individuals to decide whether or not to seek medical help or adapt their lifestyle. In addition, it can be used in clinical settings and research. The aim of this series of studies was to develop and validate a short questionnaire to assess perceived immune functioning. Five surveys were conducted among Dutch and International young healthy adults (18&ndash, 30 years old), and two others among older age groups with various health complaints. For the first study, an existing immune functioning scale was modified and elaborated resulting in 23 immune-health-related items, of which the occurrence was rated on a 5-point Likert scale. A student sample was surveyed, and the results were used to shorten the 23-item listing into a 7-item scale with a predictive validity of 85%. Items include &ldquo, sudden high fever&rdquo, &ldquo, diarrhea&rdquo, headache&rdquo, skin problems (e.g., acne and eczema)&rdquo, muscle and joint pain&rdquo, common cold&rdquo, and &ldquo, coughing&rdquo, The scale is named Immune Status Questionnaire (ISQ), and it aims to assess perceived immune status over the preceding year. The second study revealed that the ISQ score correlated significantly with a 1-item perceived immune functioning (r = 0.383, p <, 0.0001). In the third study, the final Likert scale descriptors were determined (&ldquo, never&rdquo, sometimes&rdquo, regularly&rdquo, often&rdquo, (almost) always)&rdquo, The fourth study showed that the test&ndash, retest reliability of the ISQ is acceptable (r = 0.80). The fifth study demonstrated the association of ISQ scores with various neuropsychological and health correlates in an international sample, including perceived health and immune fitness, as well as levels of stress, fatigue, depression and anxiety. Study 6 demonstrated significant associations between ISQ scores and experiencing irritable bowel syndrome (IBS) symptoms in a sample of insomnia patients. Study 7 compared the effect of a dietary intervention in participants reporting &ldquo, poor health&rdquo, versus &ldquo, normal health&rdquo, It is shown that ISQ scores can differentiate between those with poor and normal health, and that an effective intervention is associated with a significant improvement in ISQ scores. Data from Study 7 were further used to determine an ISQ cut-off value for reduced immune functioning, and a direct comparison with 1-item perceived immune functioning scores enabled constructing the final scoring format of the ISQ. In conclusion, the ISQ has appropriate face, content, and construct validity and is a reliable, stable and valid method to assess the past 12 month&rsquo, s perceived immune status.
- Published
- 2019
- Full Text
- View/download PDF
3. The Association between Ethanol Elimination Rate and Hangover Severity
- Author
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Mackus, Marlou, primary, van de Loo, Aurora JAE, additional, Garssen, Johan, additional, Kraneveld, Aletta D, additional, Scholey, Andrew, additional, and Verster, Joris C, additional
- Published
- 2020
- Full Text
- View/download PDF
4. Perceived Immune Fitness, Individual Strength and Hangover Severity
- Author
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van de Loo, Aurora J. A. E., primary, Kerssemakers, Nikki, additional, Scholey, Andrew, additional, Garssen, Johan, additional, Kraneveld, Aletta D., additional, and Verster, Joris C., additional
- Published
- 2020
- Full Text
- View/download PDF
5. Differential Gender Effects in the Relationship between Perceived Immune Functioning and Autistic Traits
- Author
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Mackus, Marlou, de Kruijff, Deborah, Otten, Leila S., Kraneveld, Aletta D, Garssen, Johan, Verster, Joris, Afd Pharmacology, Pharmacology, Afd Pharmacology, and Pharmacology
- Subjects
Male ,0301 basic medicine ,immune functioning ,Adolescent ,Universities ,Autism Spectrum Disorder ,Health, Toxicology and Mutagenesis ,autism ,chemical and pharmacologic phenomena ,Significant negative correlation ,Article ,Developmental psychology ,Young Adult ,03 medical and health sciences ,Sex Factors ,0302 clinical medicine ,Immune system ,gender ,medicine ,Humans ,Young adult ,Students ,Netherlands ,Public Health, Environmental and Occupational Health ,biochemical phenomena, metabolism, and nutrition ,medicine.disease ,Phenotype ,030104 developmental biology ,Autistic traits ,Immune System Diseases ,Autism spectrum disorder ,bacteria ,Female ,Psychology ,030217 neurology & neurosurgery - Abstract
Altered immune functioning has been demonstrated in individuals with autism spectrum disorder (ASD). The current study explores the relationship between perceived immune functioning and experiencing ASD traits in healthy young adults. N = 410 students from Utrecht University completed a survey on immune functioning and autistic traits. In addition to a 1-item perceived immune functioning rating, the Immune Function Questionnaire (IFQ) was completed to assess perceived immune functioning. The Dutch translation of the Autism-Spectrum Quotient (AQ) was completed to examine variation in autistic traits, including the domains "social insights and behavior", "difficulties with change", "communication", "phantasy and imagination", and "detail orientation". The 1-item perceived immune functioning score did not significantly correlate with the total AQ score. However, a significant negative correlation was found between perceived immune functioning and the AQ subscale "difficulties with change" (r = -0.119, p = 0.019). In women, 1-item perceived immune functioning correlated significantly with the AQ subscales "difficulties with change" (r = -0.149, p = 0.029) and "communication" (r = -0.145, p = 0.032). In men, none of the AQ subscales significantly correlated with 1-item perceived immune functioning. In conclusion, a modest relationship between perceived immune functioning and several autistic traits was found.
- Published
- 2017
6. Development and Validation of the Immune Status Questionnaire (ISQ).
- Author
-
J F Wilod Versprille L, J A E van de Loo A, Mackus M, Arnoldy L, A L Sulzer T, Vermeulen SA, Abdulahad S, Huls H, Baars T, Scholey A, Kraneveld AD, Garssen J, and Verster JC
- Subjects
- Adult, Female, Humans, Male, Self-Assessment, Young Adult, Health Status, Immunity, Innate immunology, Surveys and Questionnaires standards
- Abstract
The self-assessment of perceived immune status is important, as this subjective observation leads individuals to decide whether or not to seek medical help or adapt their lifestyle. In addition, it can be used in clinical settings and research. The aim of this series of studies was to develop and validate a short questionnaire to assess perceived immune functioning. Five surveys were conducted among Dutch and International young healthy adults (18-30 years old), and two others among older age groups with various health complaints. For the first study, an existing immune functioning scale was modified and elaborated resulting in 23 immune-health-related items, of which the occurrence was rated on a 5-point Likert scale. A student sample was surveyed, and the results were used to shorten the 23-item listing into a 7-item scale with a predictive validity of 85%. Items include "sudden high fever", "diarrhea", "headache", "skin problems (e.g., acne and eczema)", "muscle and joint pain", "common cold" and "coughing". The scale is named Immune Status Questionnaire (ISQ), and it aims to assess perceived immune status over the preceding year. The second study revealed that the ISQ score correlated significantly with a 1-item perceived immune functioning (r = 0.383, p < 0.0001). In the third study, the final Likert scale descriptors were determined ("never", "sometimes", "regularly", "often" and "(almost) always)". The fourth study showed that the test-retest reliability of the ISQ is acceptable (r = 0.80). The fifth study demonstrated the association of ISQ scores with various neuropsychological and health correlates in an international sample, including perceived health and immune fitness, as well as levels of stress, fatigue, depression and anxiety. Study 6 demonstrated significant associations between ISQ scores and experiencing irritable bowel syndrome (IBS) symptoms in a sample of insomnia patients. Study 7 compared the effect of a dietary intervention in participants reporting "poor health" versus "normal health". It is shown that ISQ scores can differentiate between those with poor and normal health, and that an effective intervention is associated with a significant improvement in ISQ scores. Data from Study 7 were further used to determine an ISQ cut-off value for reduced immune functioning, and a direct comparison with 1-item perceived immune functioning scores enabled constructing the final scoring format of the ISQ. In conclusion, the ISQ has appropriate face, content, and construct validity and is a reliable, stable and valid method to assess the past 12 month's perceived immune status.
- Published
- 2019
- Full Text
- View/download PDF
7. Susceptibility to Alcohol Hangovers: The Association with Self-Reported Immune Status.
- Author
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van de Loo AJAE, Mackus M, van Schrojenstein Lantman M, Kraneveld AD, Brookhuis KA, Garssen J, Scholey A, and Verster JC
- Subjects
- Adolescent, Adult, Alcohol-Induced Disorders immunology, Alcoholic Intoxication immunology, Blood Alcohol Content, Female, Humans, Male, Netherlands epidemiology, Self Report, Surveys and Questionnaires, Young Adult, Alcohol Drinking in College, Alcohol-Induced Disorders epidemiology, Alcoholic Intoxication epidemiology, Students
- Abstract
Increasing evidence points at a role for the immune system in the genesis of the alcohol hangover. This study investigated the association between self-reported immune function and experiencing hangovers. Dutch students aged 18 to 30 years old were invited to complete an online survey. Eighteen items on immune-related complaints were completed to assess self-reported immune function. Alcohol consumption in the past month (with respect to usual consumption and the occasion of heaviest drinking) was also recorded. Subjects with an estimated blood alcohol concentration (eBAC) of 0.18% or higher on their heaviest drinking occasion in the prior month were included in the analyses. Self-reported immune function was compared between drinkers with a hangover and those who claimed to be hangover resistant. In total, of 481 subjects (79.2% women) with a mean (SD) age of 21.1 (1.9) years old were included in the analysis. Of these, 83.3% ( n = 400) reported having hangovers and 16.8% ( n = 81) claimed to be hangover resistant. Drinkers with hangovers had significantly higher self-reported overall immune function scores when compared to hangover-resistant drinkers (mean ± SD = 10.5 ± 3.6 versus 13.1 ± 4.9, p = 0.0001), indicating a poorer immune status. In conclusion, experiencing alcohol hangovers is associated with significantly poorer self-reported immune function.
- Published
- 2018
- Full Text
- View/download PDF
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