1. Cohort Profile: The Ecuador Life (ECUAVIDA) study in Esmeraldas Province, Ecuador.
- Author
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Cooper, Philip J., Chico, Martha E., Platts-Mills, Thomas AE, Rodrigues, Laura C., Strachan, David P., and Barreto, Mauricio L.
- Subjects
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BIRTH rate , *HELMINTHS , *SOILBORNE infection , *COHORT analysis , *PUBLIC health , *ACQUISITION of data , *ALLERGIES , *ASTHMA , *ECZEMA , *HELMINTHIASIS , *IMMUNITY , *LONGITUDINAL method , *PARASITIC diseases in pregnancy , *RESEARCH funding , *RURAL population , *SKIN tests , *ENVIRONMENTAL exposure - Abstract
The ECUAVIDA birth cohort is studying the impact of exposures to soil-transmitted helminth (STH) parasites and early-life microbial exposures on the development of atopy, allergic diseases and immune responses in childhood. A total of 2404 newborns were recruited between 2006 and 2009 in a public hospital serving the rural district of Quininde, Esmeraldas Province, in a tropical region of coastal Ecuador. Detailed measurements were done around the time of the birth, at 7 and 13 months and at 2 and 3 years, and data collection is ongoing at 5 and 8 years. Data being collected include questionnaires for: sociodemographic, lifestyle, psychosocial (at 4-6 years only) and dietary (at 6-7 years only) factors; childhood morbidity and clinical outcomes; stool samples for parasites; blood samples for DNA, measurements of vaccine responses and other measures of immune function/inflammation; and anthropometrics. Allergen skin prick test reactivity is done from 2 years and measures of airway function and inflammation at 8 years. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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