1. Radiation Damage in Biomolecules and Cells 3.0.
- Author
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Carante, Mario P., Ramos, Ricardo L., and Ballarini, Francesca
- Subjects
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RADIATION damage , *RADIATION protection , *BIOMOLECULES , *DOUBLE-strand DNA breaks , *IONIZING radiation , *ASTROPHYSICAL radiation , *RADIATION-induced bystander effect , *DNA damage - Abstract
This document, titled "Radiation Damage in Biomolecules and Cells 3.0," discusses the use of ionizing radiation in medicine and the various biophysical mechanisms underlying radiation effects in biological molecules and cells. The main target of radiation is DNA, but other factors such as dose rate, radiation type and energy, and cell cycle phase also play a role in the effects of radiation. The document includes experimental and theoretical works on the effects of ionizing radiation at the DNA level, as well as applications in cancer therapy and space radiation protection. It also explores the influence of DNA damage on charge transfer and repair processes, the intrinsic radiosensitivity of cell lines, and potential candidates for improving the radiosensitivity of lung cancer cells. Additionally, it predicts astronauts' doses in the event of exposure to cosmic rays during a long-term mission to Mars. [Extracted from the article]
- Published
- 2024
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