1. The Constituents of Roots and Stems of Illigera luzonensis and Their Anti-Platelet Aggregation Effects
- Author
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Ih-Sheng Chen, Chieh-Hung Huang, Yu-yi Chan, Ren-Jie Chang, Yu Fon Chen, Tian Shung Wu, Shwu-Jen Wu, and Ping Chung Kuo
- Subjects
Aporphines ,Magnetic Resonance Spectroscopy ,Platelet Aggregation ,Stereochemistry ,Molecular Conformation ,Plant Roots ,Illigera luzonensis ,Catalysis ,Article ,Inorganic Chemistry ,lcsh:Chemistry ,chemistry.chemical_compound ,Alkaloids ,Organic chemistry ,Animals ,Aporphine ,aporphine ,alkaloid ,benzenoid ,anti-platelet aggregation effect ,Physical and Theoretical Chemistry ,Molecular Biology ,lcsh:QH301-705.5 ,Spectroscopy ,Plant Stems ,Plant Extracts ,Alkaloid ,Organic Chemistry ,Ms analysis ,General Medicine ,Anti platelet ,Computer Science Applications ,Phytochemical ,chemistry ,lcsh:Biology (General) ,lcsh:QD1-999 ,Hernandiaceae ,Rabbits ,Aporphine alkaloids ,Platelet Aggregation Inhibitors - Abstract
Phytochemical investigation of the roots and stems of Illigera luzonensis afforded two new aporphine alkaloids (1) and (2), one new bisdehydroaporphine alkaloid (3), and one new benzenoid (4), along with 28 known structures. The structures of new compounds were elucidated by spectral and MS analysis. Among the isolated compounds, (1) and (4–13) were subjected into the examination for their inhibitory effects on the aggregation of washed rabbit platelets.
- Published
- 2014