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Your search keyword '"Kim, Tae-Young"' showing total 6 results
Start Over Author "Kim, Tae-Young" Journal international journal of molecular sciences
6 results on '"Kim, Tae-Young"'

3. Facilitation of Bone Healing Processes Based on the Developmental Function of Meox2 in Tooth Loss Lesion

Author

Kim, Tae-Young, primary, Park, Jae-Kyung, additional, Prasad Aryal, Yam, additional, Lee, Eui-Seon, additional, Neupane, Sanjiv, additional, Sung, Shijin, additional, Pokharel, Elina, additional, Yeon, Chang-Yeol, additional, Kim, Ji-Youn, additional, Jung, Jae-Kwang, additional, Yamamoto, Hitoshi, additional, An, Chang-Hyeon, additional, Lee, Youngkyun, additional, Sohn, Wern-Joo, additional, Jang, Il-Ho, additional, An, Seo-Young, additional, and Kim, Jae-Young, additional

Published
2020
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4. Developmental Roles of FUSE Binding Protein 1 (Fubp1) in Tooth Morphogenesis

Author

Aryal, Yam Prasad, primary, Neupane, Sanjiv, additional, Kim, Tae-Young, additional, Lee, Eui-Seon, additional, Pokhrel, Nitin Kumar, additional, Yeon, Chang-Yeol, additional, Kim, Ji-Youn, additional, An, Chang-Hyeon, additional, An, Seo-Young, additional, Park, Eui-Kyun, additional, Ha, Jung-Hong, additional, Jung, Jae-Kwang, additional, Yamamoto, Hitoshi, additional, Cho, Sung-Won, additional, Lee, Sanggyu, additional, Kim, Do-Yeon, additional, Kwon, Tae-Yub, additional, Lee, Youngkyun, additional, Sohn, Wern-Joo, additional, and Kim, Jae-Young, additional

Published
2020
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5. Signaling Modulations of miR-206-3p in Tooth Morphogenesis

Author

Neupane, Sanjiv, primary, Aryal, Yam Prasad, additional, Kim, Tae-Young, additional, Yeon, Chang-Yeol, additional, An, Chang-Hyeon, additional, Kim, Ji-Youn, additional, Yamamoto, Hitoshi, additional, Lee, Youngkyun, additional, Sohn, Wern-Joo, additional, and Kim, Jae-Young, additional

Published
2020
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6. Lower salinomycin concentration increases apoptotic detachment in high-density cancer cells.

Author

Kim JH, Kim TY, Kim HS, Hong S, and Yoon S

Subjects
Cell Differentiation drug effects, Cell Line, Tumor, Cell Proliferation drug effects, Humans, MCF-7 Cells, Time Factors, Antineoplastic Agents pharmacology, Apoptosis drug effects, Pyrans pharmacology
Abstract

The present study identified a novel salinomycin (Sal) sensitization mechanism in cancer. We tested whether Sal reduced proliferation in a high-density population by counting attached cell numbers after Sal treatment. Sal reduced proliferation in high-density cell populations. Longer exposure to Sal further reduced proliferation. Sal concentrations of 0.1 and 5 μM had similar sensitization effects, suggesting that Sal toxicity was minimal with longer exposure to a high-density cell population. The results suggest that Sal can be applied at a relatively low concentration for a longer time to overcome drug-resistant solid tumors. The 0.5 μM Sal treatment resulted in fewer attached cells than that of the 5 μM Sal treatment with a longer exposure. The lower Sal concentration mainly increased the number of easily detachable cells on the surface. In particular, 0.5 μM Sal increased cellular detachment of newly produced daughter cells. The easily-detachable cells were undergoing apoptosis. It seems that the 0.5 μM Sal treatment also increased cellular toxicity. These novel findings may contribute to the development of Sal-based therapy for patients with drug-resistant cancer or a high-density solid tumor.

Published
2012
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