Search

Your search keyword '"Santos, Tiago"' showing total 6 results
Start Over Author "Santos, Tiago" Journal international journal of molecular sciences
6 results on '"Santos, Tiago"'

1. Establishment and Comprehensive Molecular Characterization of an Immortalized Glioblastoma Cell Line from a Brazilian Patient

Author

da Silva, Fernanda F., primary, Lupinacci, Fernanda C. S., additional, Elias, Bruno D. S., additional, Beserra, Adriano O., additional, Sanematsu, Paulo, additional, Roffe, Martin, additional, Kulikowski, Leslie D., additional, Costa, Felipe D’almeida, additional, Santos, Tiago G., additional, and Hajj, Glaucia N. M., additional

Published
2023
Full Text
View/download PDF

2. Immune Checkpoint Blockade via PD-L1 Potentiates More CD28-Based than 4-1BB-Based Anti-Carbonic Anhydrase IX Chimeric Antigen Receptor T Cells

Author

de Campos, Najla Santos Pacheco, primary, de Oliveira Beserra, Adriano, additional, Pereira, Pedro Henrique Barbosa, additional, Chaves, Alexandre Silva, additional, Fonseca, Fernando Luiz Affonso, additional, da Silva Medina, Tiago, additional, dos Santos, Tiago Goss, additional, Wang, Yufei, additional, Marasco, Wayne Anthony, additional, and Suarez, Eloah Rabello, additional

Published
2022
Full Text
View/download PDF

4. Polysome Profiling of a Human Glioblastoma Reveals Intratumoral Heterogeneity

Author

Lupinacci, Fernanda Cristina Sulla, primary, Kuasne, Hellen, additional, Roffé, Martin, additional, Vassalakis, Julia Avian, additional, da Silva, Fernanda Ferreira, additional, Santos, Tiago Góss, additional, Andrade, Victor Piana, additional, Sanematsu, Paulo, additional, Martins, Vilma Regina, additional, Rogatto, Silvia Regina, additional, and Hajj, Glaucia Noeli Maroso, additional

Published
2019
Full Text
View/download PDF

6. Unconventional Secretion of Heat Shock Proteins in Cancer.

Author

Góss Santos, Tiago, Martins, Vilma Regina, and Maroso Hajj, Glaucia Noeli

Subjects
*CANCER treatment, *CANCER genetics, *HEAT shock proteins, *CANCER thermotherapy, *CELL death, *EXOSOMES, *CANCER cells
Abstract

Heat shock proteins (HSPs) are abundant cellular proteins involved with protein homeostasis. They have both constitutive and inducible isoforms, whose expression levels are further increased by stress conditions, such as temperature elevation, reduced oxygen levels, infection, inflammation and exposure to toxic substances. In these situations, HSPs exert a pivotal role in offering protection, preventing cell death and promoting cell recovery. Although the majority of HSPs functions are exerted in the cytoplasm and organelles, several lines of evidence reveal that HSPs are able to induce cell responses in the extracellular milieu. HSPs do not possess secretion signal peptides, and their secretion was subject to widespread skepticism until the demonstration of the role of unconventional secretion forms such as exosomes. Secretion of HSPs may confer immune system modulation and be a cell-to-cell mediated form of increasing stress resistance. Thus, there is a wide potential for secreted HSPs in resistance of cancer therapy and in the development new therapeutic strategies. [ABSTRACT FROM AUTHOR]

Published
2017
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results