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Start Over Descriptor "percutaneous implant" Journal international journal of molecular sciences
2 results on '"percutaneous implant"'

1. Improved Fibroblast Functionalities by Microporous Pattern Fabricated by Microelectromechanical Systems.

Author

Hongbo Wei, Lingzhou Zhao, Bangdao Chen, Shizhu Bai, and Yimin Zhao

Subjects
*FIBROBLASTS, *MICROELECTROMECHANICAL systems, *ACTIN, *OSSEOINTEGRATION, *SOFT tissue injuries, *THERAPEUTICS
Abstract

Fibroblasts, which play an important role in biological seal formation and maintenance, determine the long-term success of percutaneous implants. In this study, well-defined microporous structures with micropore diameters of 10-60 µm were fabricated by microelectromechanical systems and their influence on the fibroblast functionalities was observed. The results show that the microporous structures with micropore diameters of 10-60 µm did not influence the initial adherent fibroblast number; however, those with diameters of 40 and 50 µm improved the spread, actin stress fiber organization, proliferation and fibronectin secretion of the fibroblasts. The microporous structures with micropore diameters of 40-50 μm may be promising for application in the percutaneous part of an implant. [ABSTRACT FROM AUTHOR]

Published
2014
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2. Improved Fibroblast Functionalities by Microporous Pattern Fabricated by Microelectromechanical Systems

Author

Yimin Zhao, Hongbo Wei, Bangdao Chen, Shizhu Bai, and Lingzhou Zhao

Subjects
Stress fiber, Materials science, Nanotechnology, Article, Catalysis, Inorganic Chemistry, lcsh:Chemistry, Micro electrical mechanical systems, fibroblasts, Cell Adhesion, medicine, Humans, Physical and Theoretical Chemistry, Fibroblast, percutaneous implant, Molecular Biology, lcsh:QH301-705.5, Cells, Cultured, Spectroscopy, Cell Proliferation, Microelectromechanical systems, microporous structure, biology, Organic Chemistry, Prostheses and Implants, General Medicine, Microporous material, Micro-Electrical-Mechanical Systems, Actin cytoskeleton, Fibronectins, Computer Science Applications, Fibronectin, Actin Cytoskeleton, medicine.anatomical_structure, lcsh:Biology (General), lcsh:QD1-999, biology.protein, microelectromechanical systems, Surface modification, Porosity, surface modification, Biomedical engineering
Abstract

Fibroblasts, which play an important role in biological seal formation and maintenance, determine the long-term success of percutaneous implants. In this study, well-defined microporous structures with micropore diameters of 10–60 µm were fabricated by microelectromechanical systems and their influence on the fibroblast functionalities was observed. The results show that the microporous structures with micropore diameters of 10–60 µm did not influence the initial adherent fibroblast number, however, those with diameters of 40 and 50 µm improved the spread, actin stress fiber organization, proliferation and fibronectin secretion of the fibroblasts. The microporous structures with micropore diameters of 40–50 µm may be promising for application in the percutaneous part of an implant.

Published
2014

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