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Cardiac patients usually feel anxious because they think their most vital organs are disturbed, and they will experience death. Anxiety has a bad impact on the development of the disease. The purpose of this study was to analyze the effect of the Benson and dhikr relaxation combination on the anxiety and pulse frequency of heart patients treated in the hospital wards. Quasy experiment research design with pre-post test control group design was employed. The population in this study were all patients undergoing hospitalization in the cardiac wards. A sample of 74 patients was taken by purposive sampling technique. The intervention given was Relaxation Benson combined with dhikr. Anxiety data were taken using the Self Anxiety Rating Scale (SARS) questionnaire, while the pulse frequency data was recorded with an observation sheet. Analysis using Independent t-test with a significant value of p <0.05. The results showed a significant difference between the anxiety of the treatment group patients and the control group (p = 0,000). The frequency of the treatment and control group pulses occurred significantly (p = 0.017). Benson's Relaxation can reduce the anxiety and pulse frequency of heart patients who are treated in the Hospital. Future studies are suggested to look at the biomolecular response of the combination of Benson and dhikr relaxation. [ABSTRACT FROM AUTHOR]