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Effects of topical administration of ethanolic extract of Malvastrum Tricuspidatum ointment was studied respectively on two types of wound models in wistar rats, (i) the incision and (ii) the dead space wound model. The ointment of the ethanolic extract of Malvastrum Tricuspidatum produced significant response in both of the wound types tested. In the incision model the extract treated wounds were found to epithelialise faster and the rate of wound contraction was higher, as compared to control wounds. The extract facilitates the healing process as evidenced by increase in the tensile strength in the incision model. [ABSTRACT FROM AUTHOR]

Telmisartan is a Anti-hypertensive drugs which is insoluble in water, hence the drug may be slowly or incompletely dissolves in the gastro-intestinal tract. So the rate of dissolution and therefore its bioavailability is less (bioavailability 42%). In the present study an attempt has been made to prepare Fast Dissolving tablets of Telmisartan by using Superdisintegrants- Cross carmellose sodium, Microcrystalline cellulose and sodium starch glycolate, level of addition to increase the rate of drug release from dosage form to increase the dissolution rate and hence its bioavailability. The tablets were prepared by Direct Compression methods and the prepared blend and tablets were evaluated for their physicochemical properties and In-Vitro dissolution study. The evaluation studies were performed such as Weight Variation, Thickness, Hardness, Disintegrating Time, Wetting Time, and In-Vitro Drug Release. The Disintegration time of Fast Dissolving tablets were increased by the addition of concentration of Superdisintegrants [ABSTRACT FROM AUTHOR]