Pesticides can move off-target resulting in contamination of sensitive water bodies and causing adverse effects on inhabiting species. Through best management practices, such as the implementation of vegetative buffer strips, off-target movement of pesticides can be decreased, and compound degradation can be increased via phytoremediation. In this study, blueflag iris (Iris versicolor), broomsedge (Andropogon virginicus) and switchgrass (Panicum virgatum) were planted in soil treated with one of three commonly used pesticides. At 28, 56 and 112 days after treatment (DAT), plants were destructively harvested and analyzed for pesticide residue in soil and above-ground and below-ground vegetation using high-performance liquid chromatography (HPLC). Relative to the amount of pesticide found in planted pots compared to non-planted pots, I. versicolor was found to reduce greater atrazine in soil compared to non-planted pots at 112 DAT by 58.7%. I. versicolor was also the most capable of reducing azoxystrobin, by 86.9% compared to non-planted pots, from the soil at 112 DAT. At the same sampling time, I. versicolor and P. virgatum reduced greater imidacloprid from soil by 62.5% and 64.3% compared to non-planted pots, respectively. This information supports the recommendation for establishment of diverse plant species for optimization of phytoremediation capacities. Novelty statement While research has found that plants can absorb and remediate synthetic chemicals, this practice is only sustainable if used with native plants that require low maintenance and are tolerant to the applied substances. Various previous studies observe plants that are fast-growing, tolerant to environmental conditions, require low-maintenance, and are hardy. However, these plant species are not always suitable for any location and are often considered invasive and/or weed-like. The present research initiates a list of plant species which can be used within the southeastern United States and similar areas to phytoremediate commonly used pesticides atrazine, azoxystrobin, and imidacloprid and prevent off-target movement.