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Your search keyword '"Sulaiman, Nor Shazrina"' showing total 6 results
Start Over Author "Sulaiman, Nor Shazrina" Journal international journal of radiation oncology, biology, physics
6 results on '"Sulaiman, Nor Shazrina"'

6. Outcomes of Patients With Sinonasal Squamous Cell Carcinoma Treated With Particle Therapy Using Protons or Carbon Ions.

Author

Nomoto, Yoshihito, Toyomasu, Yutaka, Demizu, Yusuke, Matsuo, Yoshiro, Sulaiman, Nor Shazrina, Mima, Masayuki, Nagano, Fumiko, Terashima, Kazuki, Tokumaru, Sunao, Okimoto, Tomoaki, Hayakawa, Tomokatsu, Daimon, Takashi, Fuwa, Nobukazu, and Sakuma, Hajime

Subjects
*PROTON therapy, *SQUAMOUS cell carcinoma, *CANCER chemotherapy, *RADIOTHERAPY, *PROGRESSION-free survival, *IONS, *LONGITUDINAL method, *METASTASIS, *NASAL tumors, *PARANASAL sinus cancer, *PROGNOSIS, *TIME, *TREATMENT effectiveness, *RETROSPECTIVE studies
Abstract

Purpose: This retrospective study aimed to determine the clinical outcomes following particle monotherapy (ie, proton therapy [PT] or carbon ion therapy [CIT]) in patients with sinonasal squamous cell carcinoma at a single institution.Methods and Materials: Between August 2001 and March 2012, 59 patients were treated with definitive PT or CIT; none underwent chemotherapy or surgery. Of the patients, 22 (37%) had unresectable disease. PT was used in 38 patients (64%); CIT, 21 patients (36%). Almost half of the patients (n = 29, 47%) received 65.0 Gy (relative biological effectiveness) in 26 fractions.Results: The median follow-up period was 30 months (range, 8-127 months) for all patients and 65 months (range, 9-127 months) for the survivors. The 3- and 5-year overall survival rates were 56.2% and 41.6%, respectively; progression-free survival rates, 42.9% and 34.7%, respectively; and local control rates, 54.0% and 50.4%, respectively. Late toxicities of grade ≥3 occurred in 13 patients (22%).Conclusions: To our knowledge, this is the largest retrospective study of sinonasal squamous cell carcinoma treated with particle therapy alone. The efficacy of PT and CIT indicated that particle therapy can serve an important role in treating this disease. [ABSTRACT FROM AUTHOR]

Published
2018
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