1. Effects of Exercise Training on Superoxide Dismutase Gene Expression in Human Lymphocytes
- Author
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Akira Morikawa, Tsutomu Inamizu, Minoru Nagata, and Yanbai Han
- Subjects
medicine.medical_specialty ,biology ,business.industry ,Lymphocyte ,education ,VO2 max ,Superoxide dismutase ,Football club ,Maximal Voluntary Ventilation ,medicine.anatomical_structure ,Endocrinology ,Internal medicine ,Gene expression ,medicine ,biology.protein ,Physical therapy ,Maximal exercise ,business ,Training period - Abstract
This research was conducted for the purpose of studying the influence of exercise training on the level of SOD mRNA expression in human lymphocytes. 10 first-year high school boys (age 15-16), members of the high-school football club, were subjected to exercise training for a period of 3 months; using a bicycle ergometer before and after the exercise training, maximal exercise test was conducted. The subjects trained 2 hours a day, 6 days a week over the span of 3 months, as a regular part of their club activities. Blood samples were taken before and immediately after maximal exercise test before and after training, at rest and after training at the end of 1 month, 2 months and the end of the training period; expression of manganese-SOD (Mn-SOD) mRNA and copper-zinc SOD (Cu/Zn SOD) mRNA in their lymphocytes was measured. Results showed significant increases in both maximal oxygen uptake (VO2max) and maximal voluntary ventilation (MVV), (p
- Published
- 2004
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