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Start Over Author "Arenillas, Juan F" Journal international journal of stroke
7 results on '"Arenillas, Juan F"'

1. Penumbral Rescue by normobaric O = O administration in patients with ischemic stroke and target mismatch proFile (PROOF): Study protocol of a phase IIb trial

Author

Poli, Sven, primary, Mbroh, Joshua, additional, Baron, Jean-Claude, additional, Singhal, Aneesh B, additional, Strbian, Daniel, additional, Molina, Carlos, additional, Lemmens, Robin, additional, Turc, Guillaume, additional, Mikulik, Robert, additional, Michel, Patrik, additional, Tatlisumak, Turgut, additional, Audebert, Heinrich J, additional, Dichgans, Martin, additional, Veltkamp, Roland, additional, Hüsing, Johannes, additional, Graessner, Holm, additional, Fiehler, Jens, additional, Montaner, Joan, additional, Adeyemi, Adedolapo Kamaldeen, additional, Althaus, Katharina, additional, Arenillas, Juan F, additional, Bender, Benjamin, additional, Benedikt, Frank, additional, Broocks, Gabriel, additional, Burghaus, Ina, additional, Cardona, Pere, additional, Deb-Chatterji, Milani, additional, Cviková, Martina, additional, Defreyne, Luc, additional, De Herdt, Veerle, additional, Detante, Olivier, additional, Ernemann, Ulrike, additional, Flottmann, Fabian, additional, García Guillamón, Lídia, additional, Glauch, Monika, additional, Gomez-Exposito, Alexandra, additional, Gory, Benjamin, additional, Sylvie Grand, Sylvie, additional, Haršány, Michal, additional, Hauser, Till Karsten, additional, Heck, Olivier, additional, Hemelsoet, Dimitri, additional, Hennersdorf, Florian, additional, Hoppe, Julia, additional, Kalmbach, Pia, additional, Kellert, Lars, additional, Köhrmann, Martin, additional, Kowarik, Markus, additional, Lara-Rodríguez, Blanca, additional, Legris, Loic, additional, Lindig, Tobias, additional, Luntz, Steffen, additional, Lusk, Jay, additional, Mac Grory, Brian, additional, Manger, Andreas, additional, Martinez-Majander, Nicolas, additional, Mengel, Annerose, additional, Meyne, Johannes, additional, Müller, Susanne, additional, Mundiyanapurath, Sibu, additional, Naggara, Olivier, additional, Nedeltchev, Krassen, additional, Nguyen, Thanh N, additional, Nilsson, Maike A, additional, Obadia, Michael, additional, Poli, Khouloud, additional, Purrucker, Jan C, additional, Räty, Silja, additional, Richard, Sebastien, additional, Richter, Hardy, additional, Schilte, Clotilde, additional, Schlemm, Eckhard, additional, Stöhr, Linda, additional, Stolte, Benjamin, additional, Sykora, Marek, additional, Thomalla, Götz, additional, Tomppo, Liisa, additional, van Horn, Noel, additional, Zeller, Julia, additional, Ziemann, Ulf, additional, Zuern, Christine S, additional, Härtig, Florian, additional, Tuennerhoff, Johannes, additional, Hassen, Wagih Ben, additional, Benz, Thorsten, additional, Brandhorst, Ansgar, additional, Cendrero, Judith, additional, Cheng, Bastian, additional, Cuisenier, Pauline, additional, Favre-Wiki, Isabelle, additional, Garambois, Katia, additional, Jensen, Märit, additional, Guillen, Ana Nuñez, additional, Merchan, Andres Paipa, additional, Pala, Elena, additional, Pancorbo, Olalla, additional, Morenilla, Ana Penalba, additional, Garcia, Helena Quesada, additional, Richter, Vivien, additional, Schell, Maximilian, additional, Schirmer, Andrea, additional, Sibolt, Gerli, additional, Stoop, Wendy, additional, Wischmann, Johannes, additional, and Zanolini, Umberto, additional

Published
2023
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2. Global impact of COVID-19 on stroke care

Author

Nogueira, Raul G., primary, Abdalkader, Mohamad, additional, Qureshi, Muhammed M., additional, Frankel, Michael R., additional, Mansour, Ossama Yassin, additional, Yamagami, Hiroshi, additional, Qiu, Zhongming, additional, Farhoudi, Mehdi, additional, Siegler, James E., additional, Yaghi, Shadi, additional, Raz, Eytan, additional, Sakai, Nobuyuki, additional, Ohara, Nobuyuki, additional, Piotin, Michel, additional, Mechtouff, Laura, additional, Eker, Omer, additional, Chalumeau, Vanessa, additional, Kleinig, Timothy J., additional, Pop, Raoul, additional, Liu, Jianmin, additional, Winters, Hugh S., additional, Shang, Xianjin, additional, Vasquez, Alejandro Rodriguez, additional, Blasco, Jordi, additional, Arenillas, Juan F., additional, Martinez-Galdamez, Mario, additional, Brehm, Alex, additional, Psychogios, Marios-Nikos, additional, Lylyk, Pedro, additional, Haussen, Diogo C., additional, Al-Bayati, Alhamza R., additional, Mohammaden, Mahmoud H., additional, Fonseca, Luísa, additional, Luís Silva, M, additional, Montalverne, Francisco, additional, Renieri, Leonardo, additional, Mangiafico, Salvatore, additional, Fischer, Urs, additional, Gralla, Jan, additional, Frei, ,Donald, additional, Chugh, Chandril, additional, Mehta, Brijesh P., additional, Nagel, Simon, additional, Mohlenbruch, Markus, additional, Ortega-Gutierrez, Santiago, additional, Farooqui, Mudassir, additional, Hassan, Ameer E., additional, Taylor, Allan, additional, Lapergue, Bertrand, additional, Consoli, Arturo, additional, Campbell, Bruce CV, additional, Sharma, Malveeka, additional, Walker, Melanie, additional, Van Horn, Noel, additional, Fiehler, Jens, additional, Nguyen, Huy Thang, additional, Nguyen, Quoc T., additional, Watanabe, Daisuke, additional, Zhang, Hao, additional, Le, Huynh V., additional, Nguyen, Viet Q., additional, Shah, Ruchir, additional, Devlin, Thomas, additional, Khandelwal, Priyank, additional, Linfante, Italo, additional, Izzath, Wazim, additional, Lavados, Pablo M., additional, Olavarría, Veronica V., additional, Sampaio Silva, Gisele, additional, de Carvalho Sousa, Anna Verena, additional, Kirmani, Jawad, additional, Bendszus, Martin, additional, Amano, Tatsuo, additional, Yamamoto, Ryoo, additional, Doijiri, Ryosuke, additional, Tokuda, Naoki, additional, Yamada, Takehiro, additional, Terasaki, Tadashi, additional, Yazawa, Yukako, additional, Morris, Jane G., additional, Griffin, Emma, additional, Thornton, John, additional, Lavoie, Pascale, additional, Matouk, Charles, additional, Hill, Michael D., additional, Demchuk, Andrew M., additional, Killer-Oberpfalzer, Monika, additional, Nahab, Fadi, additional, Altschul, Dorothea, additional, Ramos-Pachón, Anna, additional, Pérez de la Ossa, Natalia, additional, Kikano, Raghid, additional, Boisseau, William, additional, Walker, Gregory, additional, Cordina, Steve M., additional, Puri, Ajit, additional, Luisa Kuhn, Anna, additional, Gandhi, Dheeraj, additional, Ramakrishnan, Pankajavalli, additional, Novakovic-White, Roberta, additional, Chebl, Alex, additional, Kargiotis, Odysseas, additional, Czap, Alexandra, additional, Zha, Alicia, additional, Masoud, Hesham E., additional, Lopez, Carlos, additional, Ozretic, David, additional, Al-Mufti, Fawaz, additional, Zie, Wenjie, additional, Duan, Zhenhui, additional, Yuan, Zhengzhou, additional, Huang, Wenguo, additional, Hao, Yonggang, additional, Luo, Jun, additional, Kalousek, Vladimir, additional, Bourcier, Romain, additional, Guile, Romain, additional, Hetts, Steven, additional, Al-Jehani, Hosam M., additional, AlHazzani, Adel, additional, Sadeghi-Hokmabadi, Elyar, additional, Teleb, Mohamed, additional, Payne, Jeremy, additional, Lee, Jin Soo, additional, Hong, Ji Man, additional, Sohn, Sung-Il, additional, Hwang, Yang-ha, additional, Shin, Dong Hoon, additional, Roh, Hong Gee, additional, Edgell, Randy, additional, Khatri, Rakesh, additional, Smith, Ainsley, additional, Malik, Amer, additional, Liebeskind, David, additional, Herial, Nabeel, additional, Jabbour, Pascal, additional, Magalhaes, Pedro, additional, Ozdemir, Atilla Ozcan, additional, Aykac, Ozlem, additional, Uwatoko, Takeshi, additional, Dembo, Tomohisa, additional, Shimizu, Hisao, additional, Sugiura, Yuri, additional, Miyashita, Fumio, additional, Fukuda, Hiroki, additional, Miyake, Kosuke, additional, Shimbo, Junsuke, additional, Sugimura, Yusuke, additional, Beer-Furlan, Andre, additional, Joshi, Krishna, additional, Catanese, Luciana, additional, Abud, Daniel Giansante, additional, Neto, Octavio Giansante, additional, Mehrpour, Masoud, additional, Al Hashmi, Amal, additional, Saqqur, Mahar, additional, Mostafa, Abdulrahman, additional, Fifi, Johanna T., additional, Hussain, Syed, additional, John, Seby, additional, Gupta, Rishi, additional, Sivan-Hoffmann, Rotem, additional, Reznik, Anna, additional, Sani, Achmad Fidaus, additional, Geyik, Serdar, additional, Akıl, Eşref, additional, Churojana, Anchalee, additional, Ghoreishi, Abdoreza, additional, Saadatnia, Mohammad, additional, Sharifipour, Ehsan, additional, Ma, Alice, additional, Faulder, Ken, additional, Wu, Teddy, additional, Leung, Lester, additional, Malek, Adel, additional, Voetsch, Barbara, additional, Wakhloo, Ajay, additional, Rivera, Rodrigo, additional, Barrientos Iman, Danny Moises, additional, Pikula, Aleksandra, additional, Lioutas, Vasileios-Arsenios, additional, Thomalla, Gotz, additional, Birnbaum, Lee, additional, Machi, Paolo, additional, Bernava, Gianmarco, additional, McDermott, Mollie, additional, Kleindorfer, Dawn, additional, Wong, Ken, additional, Patterson, Mary S., additional, Fiorot, Jose Antonio, additional, Huded, Vikram, additional, Mack, William, additional, Tenser, Matthew, additional, Eskey, Clifford, additional, Multani, Sumeet, additional, Kelly, Michael, additional, Janardhan, Vallabh, additional, Cornett, Oriana, additional, Singh, Varsha, additional, Murayama, Yuichi, additional, Mokin, Maxim, additional, Yang, Pengfei, additional, Zhang, Xiaoxi, additional, Yin, Congguo, additional, Han, Hongxing, additional, Peng, Ya, additional, Chen, Wenhuo, additional, Crosa, Roberto, additional, Frudit, Michel Eli, additional, Pandian, Jeyaraj D., additional, Kulkarni, Anirudh, additional, Yagita, Yoshiki, additional, Takenobu, Yohei, additional, Matsumaru, Yuji, additional, Yamada, Satoshi, additional, Kono, Ryuhei, additional, Kanamaru, Takuya, additional, Yamazaki, Hidekazu, additional, Sakaguchi, Manabu, additional, Todo, Kenichi, additional, Yamamoto, Nobuaki, additional, Sonoda, Kazutaka, additional, Yoshida, Tomoko, additional, Hashimoto, Hiroyuki, additional, Nakahara, Ichiro, additional, Cora, Elena, additional, Volders, David, additional, Ducroux, Celina, additional, Shoamanesh, Ashkan, additional, Ospel, Johanna, additional, Kaliaev, Artem, additional, Ahmed, Saima, additional, Rashid, Umair, additional, Rebello, Leticia C., additional, Pereira, Vitor Mendes, additional, Fahed, Robert, additional, Chen, Michael, additional, Sheth, Sunil A, additional, Palaiodimou, Lina, additional, Tsivgoulis, Georgios, additional, Chandra, Ronil, additional, Koyfman, Feliks, additional, Leung, Thomas, additional, Khosravani, Houman, additional, Dharmadhikari, Sushrut, additional, Frisullo, Giovanni, additional, Calabresi, Paolo, additional, Tsiskaridze, Alexander, additional, Lobjanidze, Nino, additional, Grigoryan, Mikayel, additional, Czlonkowska, Anna, additional, de Sousa, Diana Aguiar, additional, Demeestere, Jelle, additional, Liang, Conrad, additional, Sangha, Navdeep, additional, Lutsep, Helmi L., additional, Ayo-Martín, Óscar, additional, Cruz-Culebras, Antonio, additional, Tran, Anh D., additional, Young, Chang Y., additional, Cordonnier, Charlotte, additional, Caparros, Francois, additional, De Lecinana, Maria Alonso, additional, Fuentes, Blanca, additional, Yavagal, Dileep, additional, Jovin, Tudor, additional, Spelle, Laurent, additional, Moret, Jacques, additional, Khatri, Pooja, additional, Zaidat, Osama, additional, Raymond, Jean, additional, Martins, Sheila, additional, and Nguyen, Thanh, additional

Published
2021
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3. Cerebrovascular events and outcomes in hospitalized patients with COVID-19: The SVIN COVID-19 Multinational Registry

Author

Siegler, James E, primary, Cardona, Pere, additional, Arenillas, Juan F, additional, Talavera, Blanca, additional, Guillen, Ana N, additional, Chavarría-Miranda, Alba, additional, de Lera, Mercedes, additional, Khandelwal, Priyank, additional, Bach, Ivo, additional, Patel, Pratit, additional, Singla, Amit, additional, Requena, Manuel, additional, Ribo, Marc, additional, Jillella, Dinesh V, additional, Rangaraju, Srikant, additional, Nogueira, Raul G, additional, Haussen, Diogo C, additional, Vazquez, Alejandro R, additional, Urra, Xabier, additional, Chamorro, Ángel, additional, Román, Luis S, additional, Thon, Jesse M, additional, Then, Ryna, additional, Sanborn, Emma, additional, de la Ossa, Natalia P, additional, Millàn, Mònica, additional, Ruiz, Isaac N, additional, Mansour, Ossama Y, additional, Megahed, Mohammed, additional, Tiu, Cristina, additional, Terecoasa, Elena O, additional, Radu, Răzvan A, additional, Nguyen, Thanh N, additional, Curiale, Gioacchino, additional, Kaliaev, Artem, additional, Czap, Alexandra L, additional, Sebaugh, Jacob, additional, Zha, Alicia M, additional, Liebeskind, David S, additional, Ortega-Gutierrez, Santiago, additional, Farooqui, Mudassir, additional, Hassan, Ameer E, additional, Preston, Laurie, additional, Patterson, Mary S, additional, Bushnaq, Saif, additional, Zaidat, Osama, additional, and Jovin, Tudor G, additional

Published
2020
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5. Cerebrovascular events and outcomes in hospitalized patients with COVID-19: The SVIN COVID-19 Multinational Registry.

Author

Siegler, James E, Cardona, Pere, Arenillas, Juan F, Talavera, Blanca, Guillen, Ana N, Chavarría-Miranda, Alba, de Lera, Mercedes, Khandelwal, Priyank, Bach, Ivo, Patel, Pratit, Singla, Amit, Requena, Manuel, Ribo, Marc, Jillella, Dinesh V, Rangaraju, Srikant, Nogueira, Raul G, Haussen, Diogo C, Vazquez, Alejandro R, Urra, Xabier, and Chamorro, Ángel

Subjects
COVID-19, ISCHEMIC stroke, HOSPITAL patients, SARS-CoV-2, CEREBROVASCULAR disease
Abstract

Background: Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) has been associated with a significant risk of thrombotic events in critically ill patients. Aim: To summarize the findings of a multinational observational cohort of patients with SARS-CoV-2 and cerebrovascular disease. Methods: Retrospective observational cohort of consecutive adults evaluated in the emergency department and/or admitted with coronavirus disease 2019 (COVID-19) across 31 hospitals in four countries (1 February 2020–16 June 2020). The primary outcome was the incidence rate of cerebrovascular events, inclusive of acute ischemic stroke, intracranial hemorrhages (ICH), and cortical vein and/or sinus thrombosis (CVST). Results: Of the 14,483 patients with laboratory-confirmed SARS-CoV-2, 172 were diagnosed with an acute cerebrovascular event (1.13% of cohort; 1130/100,000 patients, 95%CI 970–1320/100,000), 68/171 (40.5%) were female and 96/172 (55.8%) were between the ages 60 and 79 years. Of these, 156 had acute ischemic stroke (1.08%; 1080/100,000 95%CI 920–1260/100,000), 28 ICH (0.19%; 190/100,000 95%CI 130–280/100,000), and 3 with CVST (0.02%; 20/100,000, 95%CI 4–60/100,000). The in-hospital mortality rate for SARS-CoV-2-associated stroke was 38.1% and for ICH 58.3%. After adjusting for clustering by site and age, baseline stroke severity, and all predictors of in-hospital mortality found in univariate regression (p < 0.1: male sex, tobacco use, arrival by emergency medical services, lower platelet and lymphocyte counts, and intracranial occlusion), cryptogenic stroke mechanism (aOR 5.01, 95%CI 1.63–15.44, p < 0.01), older age (aOR 1.78, 95%CI 1.07–2.94, p = 0.03), and lower lymphocyte count on admission (aOR 0.58, 95%CI 0.34–0.98, p = 0.04) were the only independent predictors of mortality among patients with stroke and COVID-19. Conclusions: COVID-19 is associated with a small but significant risk of clinically relevant cerebrovascular events, particularly ischemic stroke. The mortality rate is high for COVID-19-associated cerebrovascular complications; therefore, aggressive monitoring and early intervention should be pursued to mitigate poor outcomes. [ABSTRACT FROM AUTHOR]

Published
2021
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6. Impact of COVID-19 outbreak on ischemic stroke admissions and in-hospital mortality in North-West Spain.

Author

Meza, Herbert Tejada, Lambea Gil, Álvaro, Saldaña, Agustín Sancho, Martínez-Zabaleta, Maite, Juez, Patricia de la Riva, Martínez, Elena López-Cancio, Apilánez, María Castañón, Isasi, María Herrera, Enguita, Juan Marta, Alfonso, Mercedes de Lera, Arenillas, Juan F, Olaizola, Jon Segurola, Fernández, Juan José Timiraos, Sánchez, Joaquín, Castellanos-Rodrigo, Mar, Roel, Alexia, Menéndez, Ignacio Casado, Freijo, Mar, Rodriguez, Alain Luna, and Portilla, Enrique Palacio

Subjects
COVID-19 pandemic, HOSPITAL mortality, STROKE, COVID-19, STROKE patients
Abstract

Background and purpose: Spain has been one of the countries heavily stricken by COVID-19. But this epidemic has not affected all regions equally. We analyzed the impact of the COVID-19 pandemic on hospital stroke admissions and in-hospital mortality in tertiary referral hospitals from North-West Spain. Methods: Spanish multicenter retrospective observational study based on data from tertiary hospitals of the NORDICTUS network. We recorded the number of patients admitted for ischemic stroke between 30 December 2019 and 3 May 2020, the number of IVT and EVT procedures, and in-hospital mortality. Results: In the study period, 2737 patients were admitted with ischemic stroke. There was a decrease in the weekly mean admitted patients during the pandemic (124 vs. 173, p<0.001). In-hospital mortality of stroke patients increased significantly (9.9% vs. 6.5%, p = 0.003), but there were no differences in the proportion of IVT (17.3% vs. 16.1%, p = 0.405) or EVT (22% vs. 23%, p = 0.504). Conclusion: We found a decrease in the number of ischemic stroke admissions and an increase in in-hospital mortality during the COVID-19 epidemic in this large study from North-West Spain. There were regional changes within the network, not fully explained by the severity of the pandemic in different regions. [ABSTRACT FROM AUTHOR]

Published
2020
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7. Uric acid therapy improves the outcomes of stroke patients treated with intravenous tissue plasminogen activator and mechanical thrombectomy.

Author

Chamorro, Ángel, Amaro, Sergio, Castellanos, Mar, Gomis, Meritxell, Urra, Xabier, Blasco, Jordi, Arenillas, Juan F., Román, Luis S., Muñoz, Roberto, Macho, Juan, Cánovas, David, Marti-Fabregas, Joan, Leira, Enrique C., and Planas, Anna M.

Subjects
URIC acid, STROKE patients, TISSUE plasminogen activator, NEUROPROTECTIVE agents, THROMBOLYTIC therapy, THERAPEUTICS
Abstract

Background: Numerous neuroprotective drugs have failed to show benefit in the treatment of acute ischemic stroke, making the search for new treatments imperative. Uric acid is an endogenous antioxidant making it a drug candidate to improve stroke outcomes. Aim: To report the effects of uric acid therapy in stroke patients receiving intravenous thrombolysis and mechanical thrombectomy. Methods: Forty-five patients with proximal vessel occlusions enrolled in the URICO-ICTUS trial received intravenous recombinant tissue plasminogen activator within 4.5 h after stroke onset and randomized to intravenous 1000 mg uric acid or placebo (NCT00860366). These patients also received mechanical thrombectomy because a brain computed tomogaphy angiography confirmed the lack of proximal recanalization at the end of systemic thrombolysis. The primary outcome was good functional outcome at 90 days (modified Rankin Score 0-2). Safety outcomes included mortality, symptomatic intracerebral bleeding, and gout attacks. Results: The rate of successful revascularization was >80% in the uric acid and the placebo groups but good functional outcome was observed in 16 out of 24 (67%) patients treated with uric acid and 10 out of 21 (48%) treated with placebo (adjusted Odds Ratio, 6.12 (95% CI 1.08-34.56)). Mortality was observed in two out of 24 (8.3%) patients treated with uric acid and one out of 21 (4.8%) treated with placebo (adjusted Odds Ratio, 3.74 (95% CI 0.06-226.29)). Symptomatic cerebral bleeding and gout attacks were similar in both groups. Conclusions: Uric acid therapy was safe and improved stroke outcomes in stroke patients receiving intravenous thrombolysis followed by thrombectomy. Validation of this simple strategy in a larger trial is urgent. [ABSTRACT FROM AUTHOR]

Published
2017
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