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Summary: In this paper, we develop a fully parametric quantile regression model based on the generalised three‐parameter beta (GB3) distribution. Beta regression models are primarily used to model rates and proportions. However, these models are usually specified in terms of a conditional mean. Therefore, they may be inadequate if the observed response variable follows an asymmetrical distribution. In addition, beta regression models do not consider the effect of the covariates across the spectrum of the dependent variable, which is possible through the conditional quantile approach. In order to introduce the proposed GB3 regression model, we first reparameterise the GB3 distribution by inserting a quantile parameter, and then we develop the new proposed quantile model. We also propose a simple interpretation of the predictor–response relationship in terms of percentage increases/decreases of the quantile. A Monte Carlo study is carried out for evaluating the performance of the maximum likelihood estimates and the choice of the link functions. Finally, a real COVID‐19 dataset from Chile is analysed and discussed to illustrate the proposed approach. [ABSTRACT FROM AUTHOR]

Summary: The binomial proportion is a classic parameter with many applications and has also been extensively studied in the literature. By contrast, the reciprocal of the binomial proportion, or the inverse proportion, is often overlooked, even though it also plays an important role in various fields. To estimate the inverse proportion, the maximum likelihood method fails to yield a valid estimate when there is no successful event in the Bernoulli trials. To overcome this zero‐event problem, several methods have been introduced in the previous literature. Yet to the best of our knowledge, there is little work on a theoretical comparison of the existing estimators. In this paper, we first review some commonly used estimators for the inverse proportion, study their asymptotic properties, and then develop a new estimator that aims to eliminate the estimation bias. We further conduct Monte Carlo simulations to compare the finite sample performance of the existing and new estimators, and also apply them to handle the zero‐event problem in a meta‐analysis of COVID‐19 data for assessing the relative risks of physical distancing on the infection of coronavirus. [ABSTRACT FROM AUTHOR]

Summary: The scientific rigor and computational methods of causal inference have had great impacts on many disciplines but have only recently begun to take hold in spatial applications. Spatial causal inference poses analytic challenges due to complex correlation structures and interference between the treatment at one location and the outcomes at others. In this paper, we review the current literature on spatial causal inference and identify areas of future work. We first discuss methods that exploit spatial structure to account for unmeasured confounding variables. We then discuss causal analysis in the presence of spatial interference including several common assumptions used to reduce the complexity of the interference patterns under consideration. These methods are extended to the spatiotemporal case where we compare and contrast the potential outcomes framework with Granger causality and to geostatistical analyses involving spatial random fields of treatments and responses. The methods are introduced in the context of observational environmental and epidemiological studies and are compared using both a simulation study and analysis of the effect of ambient air pollution on COVID‐19 mortality rate. Code to implement many of the methods using the popular Bayesian software OpenBUGS is provided. [ABSTRACT FROM AUTHOR]

Summary: Multi‐compartment models have been playing a central role in modelling infectious disease dynamics since the early 20th century. They are a class of mathematical models widely used for describing the mechanism of an evolving epidemic. Integrated with certain sampling schemes, such mechanistic models can be applied to analyse public health surveillance data, such as assessing the effectiveness of preventive measures (e.g. social distancing and quarantine) and forecasting disease spread patterns. This review begins with a nationwide macromechanistic model and related statistical analyses, including model specification, estimation, inference and prediction. Then, it presents a community‐level micromodel that enables high‐resolution analyses of regional surveillance data to provide current and future risk information useful for local government and residents to make decisions on reopenings of local business and personal travels. r software and scripts are provided whenever appropriate to illustrate the numerical detail of algorithms and calculations. The coronavirus disease 2019 pandemic surveillance data from the state of Michigan are used for the illustration throughout this paper. [ABSTRACT FROM AUTHOR]

Summary: Small area estimation (SAE) entails estimating characteristics of interest for domains, often geographical areas, in which there may be few or no samples available. SAE has a long history and a wide variety of methods have been suggested, from a bewildering range of philosophical standpoints. We describe design‐based and model‐based approaches and models that are specified at the area level and at the unit level, focusing on health applications and fully Bayesian spatial models. The use of auxiliary information is a key ingredient for successful inference when response data are sparse, and we discuss a number of approaches that allow the inclusion of covariate data. SAE for HIV prevalence, using data collected from a Demographic Health Survey in Malawi in 2015–2016, is used to illustrate a number of techniques. The potential use of SAE techniques for outcomes related to coronavirus disease 2019 is discussed. [ABSTRACT FROM AUTHOR]