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Start Over Author "Stacia Merkel Kraus" Journal international wound journal
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1. A randomised controlled 8-week crossover clinical evaluation of the 3M™ Coban™ 2 Layer Compression System versus Profore™ to evaluate the product performance in patients with venous leg ulcers

Author

Andrea McIntosh, Keith G Harding, Alexander M. Reyzelman, Stacia Merkel Kraus, Laura Shafer, Michael S Miller, Alain Brassard, Christine Moffatt, Terry Treadwell, Shelley-Ann Walters, Patricia Elaine Price, Mark Collier, Gary Sibbald, and Lynfa Edwards

Subjects
Male, medicine.medical_specialty, Compression Bandage, Dermatology, Venous leg ulcer, Varicose Ulcer, law.invention, Cohort Studies, Randomized controlled trial, Quality of life, law, medicine, Clinical endpoint, Humans, Aged, Wound Healing, Cross-Over Studies, business.industry, Original Articles, Equipment Design, Middle Aged, medicine.disease, Crossover study, Surgery, Exact test, Treatment Outcome, Patient Satisfaction, Quality of Life, Female, business, Stockings, Compression, Bandage
Abstract

This study compared a two‐layer (Coban™ 2 Layer) and a four‐layer (Profore™) compression bandage system in venous leg ulcer patients. Participants (n = 81) were enrolled into an 8‐week, randomised, open‐label, ten‐centre, crossover clinical trial. The primary endpoint was bandage slippage measured at each dressing change. Secondary endpoints included wound healing, health‐related quality of life (HRQoL) and patient preference. Mean slippage estimated from a mixed analysis of variance model (697 visits) was 2·48 cm for the two‐layer system and 4·17 cm for the four‐layer system (P

Published
2008
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