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Start Over Descriptor "aurantosides" Journal issn: 1660-3397
1 results on '"aurantosides"'

1. Aurantoside L, a New Tetramic Acid Glycoside with Anti-Leishmanial Activity Isolated from the Marine Sponge Siliquariaspongia japonica

Author

Oyadomari, Yasumoto, Goto, Yasuyuki, Suganuma, Keisuke, Kawazu, Shin Ichiro, Becking, Leontine E., Fusetani, Nobuhiro, Nakao, Yoichi, Oyadomari, Yasumoto, Goto, Yasuyuki, Suganuma, Keisuke, Kawazu, Shin Ichiro, Becking, Leontine E., Fusetani, Nobuhiro, and Nakao, Yoichi

Abstract

A new tetramic acid glycoside, aurantoside L (1), was isolated from the sponge Siliquariaspongia japonica collected at Tsushima Is., Nagasaki Prefecture, Japan. The structure of aurantoside L (1) composed of a tetramic acid bearing a chlorinated polyene system and a trisaccharide part was elucidated using spectral analysis. Aurantoside L (1) showed anti-parasitic activity against L. amazonensis with an IC50 value of 0.74 µM.

Published
2024

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