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2. Role of PIWI‐interacting RNAs on cell survival: Proliferation, apoptosis, and cycle.

Author

Zeng, Qian, Wan, Hengquan, Zhao, Simin, Xu, Haiqiang, Tang, Tingting, Oware, Kwabena Agyare, and Qu, Shunlin

Subjects
APOPTOSIS, CELLULAR control mechanisms, RNA, CELL growth, NON-coding RNA
Abstract

PIWI‐interacting RNAs (piRNAs) are a kind of non‐coding small RNAs, which play a biological role by specifically binding to PIWI proteins. Studies have demonstrated that piRNAs play a significant role in germline cell growth by repressing transposable elements, especially in the regulation of DNA methylation. Recently increasing evidence revealed that piRNAs involved in the regulation of cell proliferation, apoptosis, and cycle; however, the mechanism of piRNAs is unclear. This review summarizes the research progress regarding the roles of piRNAs in the cell proliferation, apoptosis, and cycle. [ABSTRACT FROM AUTHOR]

Published
2020
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