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This paper attempts to identify dominating factors that drive e-governance collaboration and propose a conceptual research framework for its testing and validation. A questionnaire-based survey has been conducted to obtain expert opinions. A qualitative research tool, total interpretive structural modelling (TISM), has been applied for conducting the analysis. Four TISM models namely, TISM-I, TISM-II, TISM-III and TISM-IV are developed. TISM-I contains three macro drivers of e-governance collaboration, i.e. 'Valuecreation', 'Cost-effectiveness', and 'Technology-usage'. The outcome of this model reveals 'Cost-effectiveness' as the dominating factor. TISM-II consists of six micro constituents of 'Value-creation' wherein 'Enhanced service delivery' has emerged as dominant constituent. TISM-III comprises four micro constituents of 'Cost-effectiveness' wherein 'Savings of money paid to middlemen' has emerged as the dominant one. TISM-IV comprises six micro constituents amongst which 'Usefulness of e-governance services' has emerged as dominant. The study has implications for practitioners as well as researchers.