Search

An editorial expresses views on the Alliance trial led by Chen and colleagues, indicating that despite rigorous methods, the trial showed no improvement in invasive disease-free survival among high-risk breast cancer patients with daily aspirin use, raising questions about communication of negative results, potential benefits of aspirin for other purposes, timing of aspirin use, age dynamics, biological aging, and health equity in clinical trial recruitment.

An editorial discusses the postmarketing vaccine safety assessments conducted by the US FDA and CDC following the emergency use authorization of COVID-19 vaccines. It identifies potential adverse events associated with vaccine receipt, particularly concerning a safety signal related to ischemic stroke after receiving a COVID-19 bivalent mRNA vaccine, especially when given concomitantly with a high-dose or adjuvanted influenza vaccine.

The article offers information on the use of RNA injection every 6 months to improve adherence and lower blood pressure in patients with hypertension. Topics include the significance of hypertension as a leading risk factor for various cardiovascular diseases, the challenges in achieving goal blood pressure, and the impact of nonadherence to antihypertensive treatment, which accounts for a significant portion of cases of apparent treatment-resistant hypertension.

This Viewpoint discusses the need to protect participants in clinical research and the opportunity to address this issue as the World Medical Association works to revise its Declaration of Helsinki, which governs medical research ethics. [ABSTRACT FROM AUTHOR]

The article offers information on the increase in young people seeking permanent contraception, such as tubal ligations or vasectomies, following the US Supreme Court's decision in Dobbs v Jackson Women's Health Organization.

If a physician is acting on behalf of or reporting to any third parties with respect to the care of a patient, the physician must inform the patient accordingly at the outset and, where appropriate, during the course of any interactions. If any aspect of caring for the patient is beyond the capacity of a physician, the physician must consult with or refer the patient to another appropriately qualified physician or health professional who has the necessary capacity. Editorial One of the central missions of the World Medical Association (WMA) in its role as the global organization of physicians is to ensure the highest possible standard of ethical practice of the medical profession. The physician should respect colleagues' patient-physician relationships and not intervene unless requested by either party or needed to protect the patient from harm. [Extracted from the article]

The article discusses a study on the potential benefits of using a salt substitute instead of table salt, showing a reduction in all-cause and cardiovascular mortality based on a meta-analysis of 16 randomized clinical trials involving over 35,000 participants, primarily from China or Taiwan.

The article focuses on the association between high blood glucose and triglyceride levels and the risk of mental health conditions, as well as the potential implications for early diagnosis and prevention.

The article highlights the concerning impact of medical debt on the health and mortality of individuals in the U.S., with increased debt linked to poorer physical and mental health outcomes as well as higher rates of premature death from various causes.

The article discusses a cohort study involving 1.9 million US veterans from the Afghanistan and Iraq wars, revealing that moderate or severe traumatic brain injuries (TBIs), as well as penetrating TBIs, were associated with a significantly higher risk of brain cancer.

The article focuses on the rise of ciprofloxacin-resistant meningococcal disease cases, prompting the U.S. Centers for Disease Control and Prevention (US CDC) to issue prevention guidance, as diagnosed cases increased from about annually between 2011 and 2018 to roughly 10 per year since 2019.

This Medical News feature examines the possible health consequences of making daylight saving time permanent. [ABSTRACT FROM AUTHOR]

The article emphasizes the growing distance in healthcare due to technological advancements, including telemedicine and AI (artificial intelligence) driven tools, and highlights the diminishing reliance on physical exams and human connection.

The poem "Even Joy" by Fred H. Reinhart is presented. First Line: Since her birth with half a brain; Last Line: For a time we are miraculous.

The article focuses on the long-term risks of adverse pregnancy outcomes on mortality rates among pregnant individuals, suggesting the need for early preventive evaluation and long-term clinical follow-up.

The article highlights discussions on various topics such as the prognostic value of cardiovascular biomarkers, endpoints in cancer screening trials, recommendations from the USPSTF on breast cancer screening, and the prevalence of long COVID among U.S. adults.

The article focuses on the recent finalization of a rule by the U.S. Centers for Medicare & Medicaid Services (CMS) that establishes minimum staffing requirements for nursing homes, aimed at ensuring safe and high-quality care for residents.

The article focuses on the potential impact of proposed policy changes, such as raising the eligibility age for Medicare and implementing work requirements for Medicaid coverage, on both health outcomes and government savings.

The article highlights a study, revealing broader risks associated with antipsychotic use in dementia patients, emphasizing the importance of prioritizing non-drug treatments and minimizing antipsychotic use when necessary.

The article offers information on an imaging approach that tracked subtle changes linked with mild traumatic brain injury (TBI).

The article offers information on a study linking stigma in medical records to diagnostic errors.

The article offers information on how exercise might lower the risk of heart disease by reducing stress in the brain.

The article offers information on Nigeria's rollout of the Men5CV vaccine, the world's first one-dose vaccine that protects against 5 major strains of meningococcus bacteria.

The article offers information on a systematic review and meta-analysis indicating that 67% of currently unhoused individuals have mental health disorders, based on studies mainly from Canada, Germany, and the US.

The article offers information on a report by the National Academies of Sciences, Engineering, and Medicine that reviewed evidence for potential harms associated with the Pfizer-BioNTech and Moderna COVID-19 vaccines.

The article focuses on addressing concerns raised by Drs. Palma and Kaufmann regarding the management of orthostatic hypotension, highlighting the importance of individualized treatment while cautioning against deprescribing antihypertensives en masse for older adults with hypertension.

The article focuses on optimizing the allocation of heart transplants, highlighting challenges in balancing beneficence and justice. Topics include the evolution of allocation systems, the dilemma faced by physicians in determining medical urgency, and the transition towards a continuous distribution model for heart transplant allocation based on objective criteria.

The article raises concerns about potential ascertainment bias in a recent study on physical activity and dementia, pointing out that the reliance on death certificates or hospitalization for dementia diagnosis might lead to an association between physical activity.

The article focuses on questioning the premature conclusion that Rh testing and immunoglobulin are no longer necessary following first-trimester termination of pregnancy, arguing that the study's threshold for Rh sensitization lacks consideration for previous pregnancies.

The article criticizes a recent study, emphasizing that it is premature to conclude that Rh testing and immunoglobulin are no longer necessary following first-trimester termination of pregnancy, highlighting methodological concerns, such as the use of a specific threshold for fetal red blood cells.

An editorial is presented the chronic illness of gout, emphasizing its underappreciation and poor understanding, while discussing the challenges in using serum urate as a biomarker for gout severity and treatment response. Topics include the association between baseline serum urate levels and the risk of gout flares, limitations of the study, and growing evidence linking serum urate levels with clinical outcomes.

The article discusses a study on touch interventions, revealing that people who received touch, including massage or skin-to-skin contact, experienced reductions in pain, depression, and anxiety, suggesting the systematic employment of touch interventions for health improvement.

The article discusses research by Henry T. Ricketts, MD, reported in the JAMA issue dated 1974, on the proliferation of acronyms in medical science, focusing on the challenges posed by acronyms ending in "x" and their ambiguity in denoting singular or plural entities, such as "Medex," leading to confusion in communication and grammatical structure.

The article discusses a study on the risk of second primary breast cancer in young patients without genetic risk factors, indicating a low likelihood of recurrence over 10 years, published in the journal "JAMA Oncology."

The article discusses a study on the short-term safety of psilocybin treatment for anxiety or depression, indicating that most adverse effects were manageable and improved within 1 to 2 days, based on a meta-analysis of 6 studies involving over 500 participants, published in JAMA Network Open.

A correction to the article "Pharmacotherapy for Alcohol Use Disorder" in the March 5, 2024, issue of JAMA is presented, addressing the incorrect degree listing for Wenming Shi.

A correction to the article "Lower vs Higher Oxygenation Target and Days Alive Without Life Support in COVID-19: The HOT-COVID Randomized Clinical Trial" in the April 9, 2024, issue of JAMA is presented, addressing several data errors related to the risk ratio for death by day 90.

The poem "Toward the End of My Dad's Life We Go Back to Arguing, and Soon After He Dies, I Break My Elbow" by Jessica Greenbaum is presented. First Line: Bone chips of circumstance-not the whole frame; Last Line: though misplaced parts were rarely lost for good.