1. High Prevalence of G12 Human Rotaviruses in Children with Gastroenteritis in Myanmar
- Author
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Keiji Oguma, Than Htut, Mo Mo Win, Koki Taniguchi, Hlaing Myat Thu, Takao Tsuji, Sa Van Nguyen, Satoshi Komoto, Kyaw Zin Thant, Kyoko Higo-Moriguchi, Kouji Umeda, Theingi Win Myat, Htun Naing Oo, Khaing Win Htun, Shofiqur Rahman, Yi Yi Myint, and Tomihiko Ide
- Subjects
0301 basic medicine ,Microbiology (medical) ,Male ,Rotavirus ,Genotype ,Rotavirus Infections ,Myanmar ,Biology ,medicine.disease_cause ,Microbiology ,03 medical and health sciences ,Feces ,Human rotavirus ,medicine ,Prevalence ,Humans ,Typing ,Antigens, Viral ,Phylogeny ,High prevalence ,Reverse Transcriptase Polymerase Chain Reaction ,Infant ,General Medicine ,Acute gastroenteritis ,Virology ,Gastroenteritis ,030104 developmental biology ,Infectious Diseases ,Child, Preschool ,RNA, Viral ,Capsid Proteins ,Female - Abstract
Human rotavirus samples from 54 children with acute gastroenteritis in Myanmar in 2011 were subjected to reverse transcription-PCR to determine their G and P types. On G typing, G2 (24/54; 44.4%) was found to be the most prevalent, followed by G12 (17/54; 31.5%) and G1 (1/54; 1.9%). Mixed cases with G2 and G12 were found in 12 of the 54 (22.2%) samples. On P typing, P[4] was found to be the most predominant (29/54; 53.7%), followed by P[8] (17/54; 31.5%) and P[6] (4/54; 7.4%). Mixed cases with P[4] and P[8] were detected in 4 of 54 (7.4%) samples. Thus, occurrence of G2 and unusual G12 in high proportions was characteristic of human rotaviruses in Myanmar in this study setting.
- Published
- 2015