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Your search keyword '"HARUO KAMIYA"' showing total 2 results
Start Over Author "HARUO KAMIYA" Journal japanese journal of medicine
2 results on '"HARUO KAMIYA"'

1. A case of primary hypoparathyroidism complicated by heart failure

Author

Toshiki Mano, Atusi Suzuki, Youko Imamura, Haruhiko Hasegawa, Haruo Kamiya, Setsuyo Kawakita, and Noriyuki Tani

Subjects
medicine.medical_specialty, Cardiac Catheterization, Hypoparathyroidism, medicine.medical_treatment, Biopsy, Heart Ventricles, Prednisolone, Doppler echocardiography, Asymptomatic, Calcium Carbonate, Furosemide, Internal medicine, medicine, Humans, Cardiac catheterization, Aged, Heart Failure, medicine.diagnostic_test, E/A ratio, Hypocalcemia, business.industry, Myocardium, Cardiac muscle, General Medicine, medicine.disease, Echocardiography, Doppler, medicine.anatomical_structure, Heart failure, cardiovascular system, Cardiology, Female, medicine.symptom, business, Artery
Abstract

We report a case of hypocalcemic heart failure without underlying myocardial disease. Two-dimensional and Doppler echocardiography revealed dilatation and impaired contraction of the left ventricle, but did not show any valvular dysfunction. Cardiac catheterization showed a normal coronary artery, and cardiac muscle biopsy showed morphological changes in mitochondoria and endoplasmic reticulum, which may be due to metabolic changes. This patient was asymptomatic after the serum calcium concentration was normalized.

Published
1991

2. Leukotoxin, 9, 10-epoxy-12-octadecenoate: a possible responsible factor in circulatory shock and disseminated intravascular coagulation

Author

Miyoshi Ohno, Mika Hayakawa, Satoru Sugiyama, Yoshihiro Hanaki, Haruo Kamiya, and Takayuki Ozawa

Subjects
Adult, Free Radicals, Leukocytosis, Neutrophils, medicine.medical_treatment, Shock, Cardiogenic, Pharmacology, Postoperative Complications, Renal Dialysis, Streptococcal Infections, Hemofiltration, medicine, Coagulation testing, Endocarditis, Humans, Disseminated intravascular coagulation, Heart Failure, Chemistry, General Medicine, Endocarditis, Bacterial, Disseminated Intravascular Coagulation, Middle Aged, medicine.disease, Cardiopulmonary Resuscitation, Cardiac Tamponade, Linoleic Acids, Shock (circulatory), Heart Valve Prosthesis, Circulatory system, Immunology, Female, Hemodialysis, medicine.symptom
Abstract

We previously demonstrated that neutrophils biosynthesize the Iinoleate epoxide, 9, 10-epoxy-12-octadecenoate, from Iinoleate and hydroxyl radical. This epoxide is highly cytotoxic, and has been termed leukotoxin. We detected leukotoxin in plasma from two patients with infectious endocarditis and circulatory shock. Maximal leukotoxin levels were 580 nmol/ml and 880 nmol/ml, respectively. The leukotoxin levels were affected by hemodialysis or hemofiltration. Disseminated intravascular coagulation was confirmed by blood coagulation studies in these two patients. Leukocytosis was also observed in these patients. In contrast, leukotoxin was not detected in plasma of normal volunteers. Accordingly, leukotoxin synthesized by recruited neutrophils might be a contributory factor in circulatory shock.

Published
1991

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