1. Incidence and prevalence of primary biliary cholangitis in the Netherlands – A nationwide cohort study
- Author
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Rozanne C. de Veer, Maria C.B. van Hooff, Ellen Werner, Ulrich Beuers, Joost P.H. Drenth, Frans J.C. Cuperus, Bart van Hoek, Bart J. Veldt, Michael Klemt-Kropp, Suzanne van Meer, Robert C. Verdonk, Hajo J. Flink, Jan Maarten Vrolijk, Tom J.G. Gevers, Cyriel Y. Ponsioen, Martijn J. ter Borg, Khalida Soufidi, Femke Boersma, Hendrik J.M. de Jonge, Frank H.J. Wolfhagen, L.C. Baak, Susanne L. Onderwater, Jeroen D. van Bergeijk, Paul G. van Putten, Gijs J. de Bruin, Rob P.R. Adang, Maria N. Aparicio-Pages, Wink de Boer, Frank ter Borg, Hanneke van Soest, Harry L.A. Janssen, Bettina E. Hansen, Nicole S. Erler, Adriaan J. van der Meer, Sunje Abraham, Huseyin Aktas, Yasser A. Alderlieste, L. (Bert) C. Baak, Martine A.M.C. Baven-Pronk, A. (Sander) van der Beek, Frank C. Bekkering, Menno Beukema, Kirsten Boonstra, Pieter C.J. ter Borg, Paul J. Bus, Djuna L. Cahen, Marcel Cazemier, Lisette J.H. van Dam, Maaike J. Denters, Ludger S.M. Epping, Philip W. Friederich, Nicole F.M. van Gerven, Sven J. van den Hazel, Maria C. van Hooff, Daphne M. Hotho, Matthias C. Jurgens, J.(Netty) van Kemenade, Marjo J. Kerbert-Dreteler, Ingrid C.A.W. Konings, Sander de Kort, Edith M.M. Kuiper, Johan P.H. Kuyvenhoven, Leendert H. Oterdoom, Janne E. van Rooij, Robert Roomer, Johannes Schmidt-Böhmer, Stephan Schmittgens, Tim C.M.A. Schreuder, Jerome Sint Nicolaas, Stephan H.C. van Stiphout, Hans H.K. Thio, Merel M. Tielemans, Sigrid Vandebosch, J. Marleen de Vree, Elsemieke de Vries, Anne Vrieze, Laurens A. van der Waaij, and Ulrike de Wit
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Primary biliary cholangitis ,Incidence ,Prevalence ,Diseases of the digestive system. Gastroenterology ,RC799-869 - Abstract
Background & Aims: Although primary biliary cholangitis (PBC) is considered a rare disorder, accurate determination of its incidence and prevalence remains challenging due to limited comprehensive population-based registries. We aimed to assess the incidence and prevalence of PBC in the Netherlands over time through the nationwide Dutch PBC Cohort Study (DPCS). Methods: DPCS retrospectively included every identifiable patient with PBC in the Netherlands from 1990 onwards in all 71 Dutch hospitals. Incidence and prevalence were assessed between 2008-2018 by Poisson regression between sex and age groups over time. Results: On the 1st of January 2008, there were 1,458 patients with PBC in the Netherlands. Between 2008-2018, 2,187 individuals were newly diagnosed, 46 were transplanted and 468 died. The yearly incidence of PBC in 2008 was 1.38, increasing to 1.74 per 100,000 persons in 2018. When compared to those aged
- Published
- 2024
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