1. Role of Tranexamic Acid (Topical and Intravenous) on blood loss in uncomplicated laparoscopic cholecystectomy-Prospective Study.
- Author
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Abrol, Surbhi, Chrungoo, Inakshi, Chrungoo, R. K., Mehta, Nandita, Mehta, K. S., and Bali, H. S.
- Subjects
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TRANEXAMIC acid , *LAPAROSCOPIC surgery , *SURGICAL complications , *OPERATIVE surgery , *HOSPITAL patients , *HEMATOCRIT - Abstract
Backgroud and Purpose: Despite advances in surgical technique, excess bleeding remains a major complication associated with surgery and contributes to poor clinical outcomes. A haemostatic agent with broad applicability and minimal adverse effects such as TXA is attractive as a way to control pathologic haemorrhage. Data for its use in L.C is limited. A study to review the use of TXA in controlling bleeding in uncomplicated L.C, measured in terms of drain output, preoperative and postoperative hemoglobin and hematocrit and hospital stay related to bleeding. Materials and Method: Patients were randomly divided into 4 groups of 25 patients each by Group A: receiving 10 ml I/v TXA, 30 min prior to surgery and 10ml Topical NS, Group B: receiving I.v dose of 10ml of NS, 30 min prior to surgery and 10ml TXA topically, Group C: receiving 10 ml i.v TXA, 30 min prior to surgery and 10mlof topical TXA intraoperatively, Group D: receiving 10 ml i.v NS, 30min. prior to surgery and 10ml topical NS intraoperatively. Results:The drain output and the hospital stay of the patients has significantly reduced. Group C (34.8 as compared to other TXA groups. Whereas in group-D: drain output was found to be significantly higher (81.08 and the hospital stay of the patient prolonged for a day as well. Thus use of TXA in uncomplicated L.C is recommended. Conclusion: We concluded from our study that the groups where TXA was used in either intravenous or topical or in both the forms. [ABSTRACT FROM AUTHOR]
- Published
- 2023