1. Transdiagnostic cognitive behavioral therapy for misophonia in youth: Methods for a clinical trial and four pilot cases.
- Author
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Lewin, Adam B., Dickinson, Sarah, Kudryk, Kelly, Karlovich, Ashley R., Harmon, Sherelle L., Phillips, Dominique A., Tonarely, Niza A., Gruen, Rinatte, Small, Brent, and Ehrenreich-May, Jill
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COGNITIVE therapy , *CLINICAL trials , *CONDITIONED response , *EMOTIONS , *RANDOMIZED controlled trials , *MENTAL illness , *EVALUATION research , *MISOPHONIA , *ANXIETY , *TREATMENT effectiveness , *TOURETTE syndrome , *RESEARCH , *RESEARCH methodology , *ANXIETY disorders , *COMPARATIVE studies - Abstract
Background: Misophonia is a condition marked by dysregulated emotions and behaviors in response to trigger sounds, often chewing, breathing, or coughing. Evidence suggests that misophonia develops in adolescence and the emotions and behaviors are a conditioned response to distress, resulting in social avoidance, stress, and family conflict. In addition, co-occurrence with other psychiatric illnesses such as anxiety, OCD, and Tourette syndrome is common. A transdiagnostic cognitive behavioral therapeutic (CBT) approach appears appropriate. There are currently no controlled studies of youth with misophonia. The current paper describes the approach to a pilot randomized, blinded family-based treatment study for youth ages 8-16 years. Preliminary results from a pilot open trial also are described.Methods: A 2-phase dual site telehealth treatment study using a transdiagnostic CBT approach, the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents (UP-C/A; Ehrenreich-May et al., 2018), is proposed. Phase 1 consisted of a 4-case pilot of UP-C/A. Phase 2 includes a randomized trial comparing the UP-C/A to a standard relaxation and education protocol.Results: Preliminary results from the pilot show modest improvements in evaluator-rated misophonia symptoms on the Clinical Global Impression Severity and Improvement scales.Limitations: There is little research to inform evidence-based practice for youth with misophonia. Study limitations include lack of standardized misophonia assessment instruments and an absence of formal diagnostic criteria.Conclusions: The current paper describes proposed methods for the first randomized controlled trial for youth with misophonia and their families along with results from a 4-case pilot. [ABSTRACT FROM AUTHOR]- Published
- 2021
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