1. Ptaquiloside, the major carcinogen of bracken fern, in the pooled raw milk of healthy sheep and goats: an underestimated, global concern of food safety
- Author
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Annamaria Sinisi, Valeria Russo, Orazio Taglialatela-Scafati, Franco Roperto, Antonella Virgilio, Salvatore Gerardo, Aldo Galeone, A. Santoro, Virgilio, Antonella, Sinisi, Annamaria, Russo, Valeria, S., Gerardo, Santoro, ADRIANO MICHELE LUIGI, Galeone, Aldo, TAGLIALATELA SCAFATI, Orazio, and Roperto, FRANCO PEPPINO
- Subjects
Food Safety ,Food chain ,chemistry.chemical_compound ,Grazing ,Animals ,Food science ,Pteridium ,Sheep ,biology ,business.industry ,Goats ,General Chemistry ,Raw milk ,biology.organism_classification ,Food safety ,Milk ,Agronomy ,chemistry ,Indans ,Carcinogens ,Pteridium aquilinum ,Fern ,General Agricultural and Biological Sciences ,Bracken ,business ,Ptaquiloside ,Sesquiterpenes - Abstract
Bracken fern (Pteridium aquilinum) is a worldwide plant containing toxic substances, which represent an important chemical hazard for animals, including humans. Ptaquiloside, 1, a norsesquiterpenoid glucoside, is the major carcinogen of bracken detected in the food chain, particularly in the milk from farm animals. To date, ptaquiloside has been shown in the milk of cows feeding on a diet containing bracken fern. This is the first study that shows the systematic detection of ptaquiloside, 1, and reports its direct quantitation in pooled raw milk of healthy sheep and goats grazing on bracken. Ptaquiloside, 1, was detected by a sensitive method based on the chemical conversion of ptaquiloside, 1, into bromopterosine, 4, following gas chromatography–mass spectrometry (GC–MS) analysis. The presence of ptaquiloside, 1, possibly carcinogenic to humans, in the milk of healthy animals is an unknown potential health risk, thus representing a harmful and potential global concern of food safety.
- Published
- 2015