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Your search keyword '"Kim, Yoon-Keun"' showing total 16 results
Start Over Author "Kim, Yoon-Keun" Journal journal of allergy and clinical immunology
16 results on '"Kim, Yoon-Keun"'

1. Extracellular vesicle–derived protein from Bifidobacterium longum alleviates food allergy through mast cell suppression

Author

Kim, Jung-Hwan, primary, Jeun, Eun-Ji, additional, Hong, Chun-Pyo, additional, Kim, Seong-Hoon, additional, Jang, Min Seong, additional, Lee, Eun-Jung, additional, Moon, Sook Jin, additional, Yun, Chang Ho, additional, Im, Sin-Hyeog, additional, Jeong, Seok-Geun, additional, Park, Beom-Young, additional, Kim, Kyong-Tai, additional, Seoh, Ju-Young, additional, Kim, Yoon-Keun, additional, Oh, Sung-Jong, additional, Ham, Jun-Sang, additional, Yang, Bo-Gie, additional, and Jang, Myoung Ho, additional

Published
2016
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4. TH2 and TH1 lung inflammation induced by airway allergen sensitization with low and high doses of double-stranded RNA

Author

Jeon, Seong Gyu, primary, Oh, Sun-Young, additional, Park, Hye-Kyung, additional, Kim, You-Sun, additional, Shim, Eun-Jin, additional, Lee, Hyun-Seung, additional, Oh, Min-Hee, additional, Bang, Boram, additional, Chun, Eun-Young, additional, Kim, Sang-Heon, additional, Gho, Yong Song, additional, Zhu, Zhou, additional, Kim, You-Young, additional, and Kim, Yoon-Keun, additional

Published
2007
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5. Recombinant basic fibroblast growth factor inhibits the airway hyperresponsiveness, mucus production, and lung inflammation induced by an allergen challenge

Author

Jeon, Seong Gyu, primary, Lee, Chun Geun, additional, Oh, Min-Hee, additional, Chun, Eun-Young, additional, Gho, Yong Song, additional, Cho, Sang-Heon, additional, Kim, Jong-Hoon, additional, Min, Kyung-Up, additional, Kim, You-Young, additional, Kim, Yoon-Keun, additional, and Elias, Jack A., additional

Published
2007
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10. Spider mite allergy in apple-cultivating farmers: European red mite (Panonychus ulmi) and two-spotted spider mite (Tetranychus urticae) may be important allergens in the development of work-related asthma and rhinitis symptoms☆☆☆

Author

Kim, Yoon-Keun, primary, Lee, Myung-Hyun, additional, Jee, Young-Koo, additional, Hong, Sung-Chul, additional, Bae, Jong-Myun, additional, Chang, Yoon-Suk, additional, Jung, Jae-Won, additional, Lee, Byung-Jae, additional, Son, Jee-Woong, additional, and Cho, Sang-Heon, additional

Published
1999
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14. Association between genetic variations of vascular endothelial growth factor receptor 2 and atopy in the Korean population.

Author

Park HW, Lee JE, Shin ES, Lee JY, Bahn JW, Oh HB, Oh SY, Cho SH, Moon HB, Min KU, Elias JA, Kim YY, and Kim YK

Subjects
Adolescent, Adult, Aged, Aged, 80 and over, Asthma epidemiology, Asthma genetics, Child, Cohort Studies, Female, Genes, Dominant, Genes, Recessive, Genetic Variation, Genotype, Haplotypes, Humans, Hypersensitivity, Immediate epidemiology, Korea epidemiology, Male, Middle Aged, Polymorphism, Single Nucleotide, Hypersensitivity, Immediate genetics, Vascular Endothelial Growth Factor Receptor-2 genetics
Abstract

Background: Vascular endothelial growth factor (VEGF) has been suggested to be a key mediator in the development of atopy and T(H)2 inflammation., Objective: We sought to evaluate the effects of variations in the gene coding VEGF receptor (VEGFR) 2 on intermediate phenotypes of asthma in the Korean population., Methods: A cohort of 2055 children and adolescents responded to a questionnaire concerning asthma symptoms and risk factors and underwent methacholine bronchial challenge and skin tests. The VEGFR2 gene, including the promoter area, was sequenced on 24 healthy subjects to discover informative single nucleotide polymorphisms (SNPs; minor allele frequency >2%). After haplotype reconstruction, 4 tagging SNPs (IVS6+54A>G, +889G>A, +1416T>A, and IVS25-92G>A) were scored. These SNPs were also scored in 480 adult asthmatic patients to verify the above genetic association study., Results: The prevalence of atopy was associated with a single SNP (+889G>A) of VEGFR2 with borderline significance (P = .048; relative risk, 1.13; 95% CI, 1.00-1.28). However, haplotype analysis showed that the atopy prevalence was strongly associated with a haplotype (AGAG) of VEGFR2 (P = .002; relative risk, 1.25; 95% CI, 1.09-1.42). As for airway hyperresponsiveness, neither individual SNPs nor haplotypes were found to be associated. Interestingly, the significant association was also found between atopy and the AGAG haplotype among adult asthmatic patients (P = .008; odds ratio, 1.66; 95% CI, 1.14-2.44)., Conclusions: The present study demonstrated that genetic variations of VEGFR2 are significantly associated with atopy in the Korean population.

Published
2006
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16. Association of beta2-adrenoreceptor polymorphisms with nocturnal cough among atopic subjects but not with atopy and nonspecific bronchial hyperresponsiveness.

Author

Kim SH, Oh SY, Oh HB, Kim YK, Cho SH, Kim YY, and Min KU

Subjects
Adult, Aged, Alleles, Female, Genotype, Haplotypes, Humans, Male, Middle Aged, Bronchial Hyperreactivity etiology, Cough etiology, Hypersensitivity etiology, Polymorphism, Genetic, Receptors, Adrenergic, beta-2 genetics
Abstract

Background: The reports from in vitro studies that beta(2)-adre-nergic receptor (B2AR) polymorphisms are associated with agonist-promoted downregulation have evoked considerable research interest for the roles of these polymorphisms to the pathogenesis of asthma., Objective: We sought to evaluate the association between asthma phenotypes and B2AR polymorphisms at 2 sites (Arg16 --> Gly16 and Gln27 --> Glu27) in the general population., Methods: Four hundred forty unrelated Korean adults were randomly selected, and asthma phenotypes were determined with a questionnaire, immunoassay, skin prick testing, and methacholine bronchial provocation testing. Genotypes of B2AR polymorphisms were determined with PCR-based methods., Results: No significant association was found between B2AR alleles and haplotypes and total IgE levels, skin test responses to aeroallergens, and bronchial responsiveness to methacholine. Among the atopic subjects, however, numbers of both Arg16 alleles and Arg16-Gln27 haplotypes were negatively associated with nocturnal cough, and in contrast, Gly16-Gln27 was positively associated with it., Conclusion: B2AR polymorphisms may play an important role in the expression of nocturnal cough in atopic subjects but not in the expression of atopy and bronchial hyperresponsiveness in a general population.

Published
2002
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