1. One-Year Evolution of Behavioral and Psychological Symptoms of Dementia in Patients Initially Hospitalized in Cognitive Behavioral Units: The EVITAL Prospective Cohort
- Author
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Florence Fabre, Magalie Freulon, Isabelle Rouch, Nicolas Auguste, Christelle Mouchoux, Pierre Krolak-Salmon, Bernard Laurent, Sophie Jacqueline, Géraldine Martin-Gaujard, Elodie Pongan, Claire Sellier, Jean-Michel Dorey, Béatrice Trombert, and Denis Federico
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Male ,medicine.medical_specialty ,Psychosis ,Longitudinal study ,Clinical Dementia Rating ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,mental disorders ,Humans ,Medicine ,Dementia ,Longitudinal Studies ,Prospective Studies ,030212 general & internal medicine ,Prospective cohort study ,Psychiatry ,Aged, 80 and over ,Psychotropic Drugs ,business.industry ,General Neuroscience ,General Medicine ,Mental Status and Dementia Tests ,medicine.disease ,Hospitalization ,Psychiatry and Mental health ,Clinical Psychology ,Mood ,Test score ,Cohort ,Disease Progression ,Linear Models ,Female ,Geriatrics and Gerontology ,Factor Analysis, Statistical ,business ,030217 neurology & neurosurgery ,Follow-Up Studies - Abstract
BACKGROUND The 2008-2012 French Alzheimer's Plan has provided hospital Cognitive and Behavioral Units (CBU) to improve the management of patients with productive behavioral and psychological symptoms of dementia (BPSD). Little is known concerning the behavioral outcome of these patients after discharge. OBJECTIVE The present study investigated the long-term evolution of BPSD over one year after CBU discharge. METHODS The EVITAL cohort included 221 participants admitted to the CBUs of 3 French hospitals. BPSD were collected using the Neuropsychiatric Inventory (NPI) at admission and 3, 6, and 12 months after hospitalization. The global NPI score evolution was assessed using a linear mixed-effect model. A four-factor model of the NPI including behavioral dyscontrol, psychosis, mood, and agitation subscores was also analyzed. RESULTS Our analysis focused on 148 patients followed up during 12 months and evaluated at each visit. The global NPI score was 48.5 (SD 21.7) at baseline, 28.8 (SD 18.7) at 3-month, 23.2 (SD 16.4) at 6-month and 20.9 (SD 15.9) at 12-month follow-up. The score significantly decreased from baseline to follow-up (F = 109.3 p
- Published
- 2017
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