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Your search keyword '"Olde Rikkert, Marcel"' showing total 13 results
Start Over Author "Olde Rikkert, Marcel" Journal journal of alzheimer's disease
13 results on '"Olde Rikkert, Marcel"'

4. Trajectories and Determinants of Quality of Life in Dementia with Lewy Bodies and Alzheimer’s Disease

Author

van de Beek, Marleen, primary, van Steenoven, Inger, additional, Ramakers, Inez H.G.B., additional, Aalten, Pauline, additional, Koek, Huiberdina L., additional, Olde Rikkert, Marcel G.M., additional, Manniën, Judith, additional, Papma, Janne M., additional, de Jong, Frank Jan, additional, Lemstra, Afina W., additional, and van der Flier, Wiesje M., additional

Published
2019
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5. Cardiorespiratory Fitness and Cognitive Function are Positively Related Among Participants with Mild and Subjective Cognitive Impairment.

Author

on behalf of the NeuroExercise Study Group, Matura, Rüdiger, Stefanie, Abeln, Vera, Stuckenschneider, Tim, Schneider, Stefan, Askew, Christopher David, Cristina Polidori, Maria, Vogt, Tobias, Krome, Andreas, Olde Rikkert, Marcel, Lawlor, Brian, Polidori, Maria Cristina, and NeuroExercise Study Group

Subjects
MILD cognitive impairment, PHYSICAL activity, COGNITIVE ability, MEMORY loss, CARDIOPULMONARY system
Abstract

Background: By 2030, about 74 million people will be diagnosed with dementia, and many more will experience subjective (SCI) or mild cognitive impairment (MCI). As physical inactivity has been identified to be a strong modifiable risk factor for dementia, exercise and physical activity (PA) may be important parameters to predict the progression from MCI to dementia, but might also represent disease trajectory modifying strategies for SCI and MCI.Objective: A better understanding of the relationship between activity, fitness, and cognitive function across the spectrum of MCI and SCI would provide an insight into the potential utility of PA and fitness as early markers, and treatment targets to prevent cognitive decline.Methods: 121 participants were stratified into three groups, late MCI (LMCI), early MCI (EMCI), and SCI based on the Montreal Cognitive Assessment (MoCA). Cognitive function assessments also included the Trail Making Test A+B, and a verbal fluency test. PA levels were evaluated with an interviewer-administered questionnaire (LAPAQ) and an activity monitor. An incremental exercise test was performed to estimate cardiorespiratory fitness and to determine exercise capacity relative to population normative data.Results: ANCOVA revealed that LMCI subjects had the lowest PA levels (LAPAQ, p = 0.018; activity monitor, p = 0.041), and the lowest exercise capacity in relation to normative values (p = 0.041). Moreover, a modest correlation between MoCA and cardiorespiratory fitness (r = 0.25; p < 0.05) was found.Conclusion: These findings suggest that during the earliest stages of cognitive impairment PA and exercise capacity might present a marker for the risk of further cognitive decline. This finding warrants further investigation using longitudinal cohort studies. [ABSTRACT FROM AUTHOR]

Published
2018
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6. Tolerability and Safety of Souvenaid in Patients with Mild Alzheimer's Disease: Results of Multi-Center, 24-Week, Open-Label Extension Study

Author

Olde Rikkert, Marcel G.M., primary, Verhey, Frans R., additional, Blesa, Rafael, additional, von Arnim, Christine A.F., additional, Bongers, Anke, additional, Harrison, John, additional, Sijben, John, additional, Scarpini, Elio, additional, Vandewoude, Maurits F.J., additional, Vellas, Bruno, additional, Witkamp, Renger, additional, Kamphuis, Patrick J.G.H., additional, and Scheltens, Philip, additional

Published
2015
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7. The Influence of Co-Morbidity and Frailty on the Clinical Manifestation of Patients with Alzheimer's Disease

Author

Oosterveld, Saskia M., primary, Kessels, Roy P.C., additional, Hamel, Renske, additional, Ramakers, Inez H.G.B., additional, Aalten, Pauline, additional, Verhey, Frans R.J., additional, Sistermans, Nicole, additional, Smits, Lieke L., additional, Pijnenburg, Yolande A., additional, van der Flier, Wiesje M., additional, Olde Rikkert, Marcel G.M., additional, and Melis, René J.F., additional

Published
2014
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9. Differences in Nutritional Status Between Very Mild Alzheimer's Disease Patients and Healthy Controls

Author

Olde Rikkert, Marcel G.M., primary, Verhey, Frans R., additional, Sijben, John W.C., additional, Bouwman, Femke H., additional, Dautzenberg, Paul L.J., additional, Lansink, Mirian, additional, Sipers, Walther M.W., additional, van Asselt, Dieneke Z.B., additional, van Hees, Anneke M.J., additional, Stevens, Martijn, additional, Vellas, Bruno, additional, and Scheltens, Philip, additional

Published
2014
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10. The Association Between APOE ε4 and Alzheimer-type Dementia Among Memory Clinic Patients is Confined to those with a Higher Education. The DESCRIPA Study

Author

Vermeiren, Angelique P.A., primary, Bosma, Hans, additional, Visser, Pieter-Jelle, additional, Zeegers, Maurice P., additional, Graff, Caroline, additional, Ewers, Michael, additional, Frisoni, Giovanni B., additional, Frölich, Lutz, additional, Hampel, Harald, additional, Jones, Roy W., additional, Kehoe, Patrick G., additional, Lenoir, Hermine, additional, Minthon, Lennart, additional, Nobili, Flavio M., additional, Olde Rikkert, Marcel, additional, Rigaud, Anne-Sophie, additional, Scheltens, Philip, additional, Soininen, Hilkka, additional, Spiru, Luiza, additional, Tsolaki, Magda, additional, Wahlund, Lars-Olof, additional, Vellas, Bruno, additional, Wilcock, Gordon, additional, Elias-Sonnenschein, Lyzel S., additional, and Verhey, Frans R.J., additional

Published
2013
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11. Real World Recruiting of Older Subjects with Mild Cognitive Impairment for Exercise Trials: Community Readiness is Pivotal.

Author

Sanders, Marit L, Stuckenschneider, Tim, Devenney, Kate E, Lawlor, Brian, Schneider, Stefan, Olde Rikkert, Marcel G M, and NeuroExercise Study Group

Subjects
RISK factors of mild cognitive impairment, HEALTH of older people, AGE factors in cognition, EXERCISE, COGNITIVE testing, SCIENTIFIC community, LIFESTYLES, PATIENT selection
Abstract

Prevention trials in subjects with mild cognitive impairment (MCI), especially lifestyle interventions, can be difficult to carry out, particularly the recruitment and retention of subjects. We experienced these challenges in our multi-site one-year exercise trial in MCI, NeuroExercise. Trial recruitment rates differed significantly across sites; the non-medical sport university site, providing free access to a range of group exercise in a sports environment, proved far more successful than memory clinics linked to hospitals. This suggests that non-medical settings and a non-medical research community facilitating physical activities may be important factors in recruitment of subjects with MCI for large prevention trials. [ABSTRACT FROM AUTHOR]

Published
2018
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13. The Association Between APOE 4 and Alzheimer-type Dementia Among Memory Clinic Patients is Confined to those with a Higher Education. The DESCRIPA Study.

Author

Vermeiren, Angelique P A, Bosma, Hans, Visser, Pieter-Jelle, Zeegers, Maurice P, Graff, Caroline, Ewers, Michael, Frisoni, Giovanni B, Frölich, Lutz, Hampel, Harald, Jones, Roy W, Kehoe, Patrick G, Lenoir, Hermine, Minthon, Lennart, Nobili, Flavio M, Olde Rikkert, Marcel, Rigaud, Anne-Sophie, Scheltens, Philip, Soininen, Hilkka, Spiru, Luiza, and Tsolaki, Magda

Published
2013
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