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Start Over Author "Chien-Jen Wang" Journal journal of analytical toxicology

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1. Quantification of Blood Betel Quid Alkaloids and Urinary 8-Hydroxydeoxyguanosine in Humans and their Association with Betel Chewing Habits.

Author

I-Chen Wu, Ping-Ho Chen, Chien-Jen Wang, Deng-Chyang Wu, Shih-Menglsai, Mu-Rong Chao, Bai-Hsiun Chen, Hei-Hwa Lee, Chien-Hung Lee, and Ying-Chin Ko

Subjects
*BETEL chewing, *QUANTITATIVE research, *ALKALOIDS, *LIQUID chromatography, *MASS spectrometry, *SERUM
Abstract

The article presents a study on the quantitative analysis of blood betel quid alkaloids and urinary 8-hydroxydeoxyguanosine (8-OH-dg) in human, along with its correlation in betel chewing habits. The study developed a liquid chromatography-tandem mass spectrometry method to examine the quantity of arecoline and arecaidine, and showed the correlation of betel quid on drawing blood and arecoline. It reveals that serum arecoline and arecaidine were measurable and good indicators of betel quid use.

Published
2010
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