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Abstract Background The use of agroindustrial by-products in ruminant nutrition to be an interesting alternative in order to reduce production costs and environmental impacts arising from the inadequate destination of residues. The initial step of beer production yields a large volume of wet brewer’s grains all year around, which is available at a low cost and has a high nutritional quality, and hence a big potential for animal production. Methods Twenty-four Suffolk non-castrated male lambs, from simple parturition were kept in individual spots and allocated to four treatments constituted by four levels of substitution of sorghum silage by WBG (i.e.0; 33.5; 66.5 and 100% of substitution). It was used roughage: concentrate rate of 50:50, based on dry matter. Results The ether extract intake increased while the acid detergent fiber intake decreased linearly (P ≤ 0.05). Substituion of sorghum silage by WBG did not change lambs’ feed DMI, daily weight gain and feed conversion. Conclusion The substitution of sorghum silage by WBG as roughage showed to be a viable alternative from the productive and economic point of view for finishing of feedlot lambs.