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• We review the state of research on human-environment interaction in Holocene China. • We demonstrate the benefits of a multidisciplinary, regionally focused approach. • We conclude datasets must be local and specific, and integrate data on multiple scales. • China is large, well-documented, and critical for understanding social-natural systems. This paper reviews recent archaeological research on human-environment interaction in the Holocene, taking continental China as its geographic focus. As China is large, geographically diverse, and exceptionally archaeologically and historically well-documented, research here provides critical insight into the functioning of social-natural systems. Based on a broad review of the field as well as recent advances and discoveries, the authors reflect on research themes including climate change and adaptive systems theory, spatial and temporal scale, anthropogenic environmental change, risk management and resilience, and integration of subdisciplines. These converge on three overarching conclusions. First, datasets relevant to climate change and ancient human-environment interaction must be as local and specific as possible, as the timing of environmental change differs locally, and the human response is highly dependent on local social and technological conditions. Second, the field still needs more robust theoretical frameworks for analyzing complex social-natural systems, and especially for integrating data on multiple scales. Third, for this work to contribute meaningfully to contemporary climate change research, effective communication of research findings to the public and to scientists in other disciplines should be incorporated into publication plans. [ABSTRACT FROM AUTHOR]