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Your search keyword '"Crast LB Jr"' showing total 2 results
Start Over Author "Crast LB Jr" Journal journal of antibiotics
2 results on '"Crast LB Jr"'

1. 3-Acylthiomethyl cephalosporins.

Author

Essery JM, Corbin U, Sprancmanis V, Crast LB Jr, Graham RG, Misco PF Jr, Willner D, McGregor DN, and Cheney LC

Subjects
Animals, Bacteria drug effects, Cephalexin pharmacology, Cephalosporins blood, Cephalosporins pharmacology, Chemical Phenomena, Chemistry, Mice, Microbial Sensitivity Tests, Sulfhydryl Compounds chemical synthesis, Time Factors, Cephalosporins chemical synthesis
Published
1974
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2. Synthesis and in vitro activity of new semi-synthetic coumermycin analogs: chemical modification at the C-3 amide.

Author

Ueda Y, Chuang JM, Crast LB Jr, and Partyka RA

Subjects
Aminocoumarins, Anti-Bacterial Agents pharmacology, Chemical Phenomena, Chemistry, Coumarins chemical synthesis, Coumarins pharmacology, Gram-Positive Bacteria drug effects, Microbial Sensitivity Tests, Structure-Activity Relationship, Anti-Bacterial Agents chemical synthesis
Abstract

Several new semi-synthetic coumermycin analogs, which carry a polar substituent at the C-3 amide moiety have been prepared. In vitro antibacterial activity of these new analogs against Gram-positive organisms, particularly methicillin-resistant strains of Staphylococci species has been described.

Published
1989
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