1. Phenolic constituents from the roots of Phyllodium pulchellum.
- Author
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Zong, Yang, Zhong, Ming, Li, Dong-Mei, Zhang, Bao-Jing, Mai, Zhen-Peng, Huo, Xiao-Kui, Huang, Shan-Shan, Zhang, Hou-Li, Wang, Chao, Ma, Xiao-Chi, Yu, Sheng-Min, and Yang, Dong-Ai
- Subjects
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SPECTROPHOTOMETRY , *CHROMATOGRAPHIC analysis , *ALDEHYDES , *ANIMAL experimentation , *CELL culture , *MASS spectrometry , *MOLECULAR structure , *NUCLEAR magnetic resonance spectroscopy , *PHARMACEUTICAL chemistry , *POLYPHENOLS , *RATS , *RESEARCH funding , *PLANT roots , *DESCRIPTIVE statistics - Abstract
Three new phenolic constituents 1–3 were obtained from the 95% ethanol extract of the roots of Phyllodium pulchellum (Leguminosae). Their structures were elucidated on the basis of spectroscopic analyses, such as NMR, UV, IR, HR-ESI-MS, and CD. Furthermore, in an in vitro bioassay, all compounds were tested for inhibitory effects against the proliferation of acetaldehyde-stimulated HSC-T6 cells, and compound 3 exhibited potent inhibitory activity with the IC50 value of 7.6 μM. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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