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Start Over Descriptor "Sperm Injections" Journal journal of assisted reproduction and genetics
3 results on '"Sperm Injections"'

1. Vitamin D as a follicular marker of human oocyte quality and a serum marker of in vitro fertilization outcome

Author

Ciepiela, Przemysław, Dulęba, Antoni J, Kowaleczko, Ewelina, Chełstowski, Kornel, and Kurzawa, Rafał

Subjects
Reproductive Medicine, Biomedical and Clinical Sciences, Infertility, Contraception/Reproduction, Complementary and Integrative Health, Clinical Research, 1.1 Normal biological development and functioning, Underpinning research, Reproductive health and childbirth, Adult, Biomarkers, Birth Rate, Embryonic Development, Female, Fertilization, Fertilization in Vitro, Follicular Fluid, Humans, Infertility, Female, Live Birth, Oocyte Retrieval, Oocytes, Oogenesis, Ovarian Follicle, Pregnancy, Pregnancy Rate, Prospective Studies, Sperm Injections, Intracytoplasmic, Vitamin D, Oocyte quality, Vitamin D [25(OH) D], Follicular fluid, ICSI, Single embryo transfer, Vitamin D [25(OH)D], Genetics, Paediatrics and Reproductive Medicine, Obstetrics & Reproductive Medicine, Reproductive medicine
Abstract

PurposeThis study investigated the relationship between the vitamin D [25(OH)D] level in individual follicles and oocyte developmental competence.MethodsA prospective cohort study in a private infertility center. Infertile women (N = 198) scheduled for intracytoplasmic sperm injection (ICSI) and a single embryo transfer (SET) provided serum samples and 322 follicular fluid (FF) specimens, each from a single follicle on the day of oocyte retrieval.ResultsFFs corresponding to successfully fertilized oocytes (following ICSI) contained significantly lower 25(OH)D level compared with those that were not fertilized (28.4 vs. 34.0 ng/ml, P = 0.001). Top quality embryos on the third day after fertilization, when compared to other available embryos, developed from oocytes collected from follicles containing significantly lower 25(OH)D levels (24.56 vs. 29.59 ng/ml, P = 0.007). Positive hCG, clinical pregnancy, and live birth rates were achieved from embryos derived from oocytes that grew in FF with significantly lower 25(OH)D levels than in follicles not associated with subsequent pregnancy. The concentration of 25(OH)D in FF in women with negative hCG was 32.23 ± 20.21 ng/ml, positive hCG 23.62 ± 6.09 ng/ml, clinical pregnancy 23.13 ± 6.09 ng/ml, and live birth 23.45 ± 6.11 ng/ml (P

Published
2018

2. Vitamin D as a follicular marker of human oocyte quality and a serum marker of in vitro fertilization outcome

Author

Antoni J. Duleba, Przemysław Ciepiela, Kornel Chełstowski, Ewelina Kowaleczko, and Rafał Kurzawa

Subjects
0301 basic medicine, Sperm Injections, Pregnancy Rate, medicine.medical_treatment, Oocyte Retrieval, Vitamin D [25(OH) D], Intracytoplasmic sperm injection, Oogenesis, 0302 clinical medicine, Human fertilization, Ovarian Follicle, Pregnancy, Follicular phase, Prospective Studies, Vitamin D, Assisted Reproduction Technologies, Birth Rate, Genetics (clinical), 030219 obstetrics & reproductive medicine, Obstetrics and Gynecology, General Medicine, ICSI (intracytoplasmic sperm injection), Intracytoplasmic, medicine.anatomical_structure, Female, Infertility, Female, Live Birth, Adult, Embryonic Development, Fertilization in Vitro, Follicular fluid, ICSI, Paediatrics and Reproductive Medicine, Andrology, 03 medical and health sciences, Oocyte quality, Vitamin D [25(OH)D], Genetics, medicine, Vitamin D and neurology, Humans, Sperm Injections, Intracytoplasmic, Obstetrics & Reproductive Medicine, Single embryo transfer, In vitro fertilisation, Single embryo transfer (SET), business.industry, medicine.disease, Oocyte, 030104 developmental biology, Reproductive Medicine, Infertility, Fertilization, Oocytes, business, Biomarkers, Developmental Biology
Abstract

PurposeThis study investigated the relationship between the vitamin D [25(OH)D] level in individual follicles and oocyte developmental competence.MethodsA prospective cohort study in a private infertility center. Infertile women (N = 198) scheduled for intracytoplasmic sperm injection (ICSI) and a single embryo transfer (SET) provided serum samples and 322 follicular fluid (FF) specimens, each from a single follicle on the day of oocyte retrieval.ResultsFFs corresponding to successfully fertilized oocytes (following ICSI) contained significantly lower 25(OH)D level compared with those that were not fertilized (28.4 vs. 34.0ng/ml, P = 0.001). Top quality embryos on the third day after fertilization, when compared to other available embryos, developed from oocytes collected from follicles containing significantly lower 25(OH)D levels (24.56 vs. 29.59ng/ml, P = 0.007). Positive hCG, clinical pregnancy, and live birth rates were achieved from embryos derived from oocytes that grew in FF with significantly lower 25(OH)D levels than in follicles not associated with subsequent pregnancy. The concentration of 25(OH)D in FF in women with negative hCG was 32.23 ± 20.21ng/ml, positive hCG 23.62 ± 6.09ng/ml, clinical pregnancy 23.13 ± 6.09ng/ml, and live birth 23.45 ± 6.11ng/ml (P

Published
2018
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3. Lower embryonic loss rates among twin gestations following assisted reproduction

Author

Giuseppe Nucera, G. B. La Sala, Andrea Gallinelli, Isaac Blickstein, Alessia Nicoli, and Maria Teresa Villani

Subjects
Male, Sperm Injections, Twins, Uterus, Abortion, Pregnancy, Medicine, Prospective Studies, Prospective cohort study, First, reproductive and urinary physiology, Genetics (clinical), media_common, Obstetrics, Singleton, Obstetrics and Gynecology, General Medicine, female genital diseases and pregnancy complications, Intracytoplasmic, Abortion, Spontaneous, Adult, Embryonic Development, Female, Humans, Maternal Age, Pregnancy Trimester, First, Sperm Injections, Intracytoplasmic, Pregnancy, Multiple, Assisted Reproduction, medicine.anatomical_structure, embryonic structures, Gestation, Pregnancy Trimester, Reproduction, therapeutics, Multiple, medicine.medical_specialty, media_common.quotation_subject, Reproductive medicine, Genetics, Gynecology, urogenital system, business.industry, Spontaneous, medicine.disease, Reproductive Medicine, business, Developmental Biology
Abstract

Purpose: To determine whether maternal age and number of transferred embryos influence early pregnancy losses in twin pregnancies compared to singletons following IVF/ICSI. Methods: We compared the pregnancy loss rates in singleton (n = 549) and twin (n = 252) gestations, stratified by maternal age (≤35 and > 35 years) and the number of transferred embryos (1–3 and 4–9). Results: Loss rates of singleton pregnancies were significantly higher than that in twins (OR 3.0, 95% CI 1.9, 4.9), especially among singletons conceived after transfer of 4–9 embryos (OR 5.0, 95% CI 2.2, 11.9). Younger mothers of twins had lower loss rates (OR 0.3, 95% CI 0.1, 0.9). Conclusion: Twins have a significantly reduced spontaneous miscarriage rate compared with singletons following IVF/ICSI. Higher implantation rates per cycle (i.e., development of twins rather than one live embryo) may represent a better capacity of the uterus for early embryonic development.

Published
2005
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