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Start Over Author "Kunz, Stefanie" Publication Type Academic Journals Journal journal of biological chemistry

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1 results on '"Kunz, Stefanie"'

1. Multiple Mechanisms of Reduced Major Histocompatibility Complex Class II Expression in Endotoxin Tolerance.

Author

Wolk, Kerstin, Kunz, Stefanie, Crompton, Nigel E.A., Volk, Hans-Dieter, and Sabat, Robert

Subjects
*MAJOR histocompatibility complex, *ENDOTOXINS, *MONOCYTES
Abstract

Focuses on the mechanism behind reduced major histocompatibility complex (MHC) class II expression in endotoxin tolerance. Effect of endotoxin priming on monocyte intracellular MHC class II; Reduction of the expression of chaperonic invariant chain; Inhibited synthesis of the major lysosomal enzyme for final cleavage of the invariant chain going along with a relative accumulation of p10.

Published
2003
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