1. Brown adipose tissue density measured by near-infrared time-resolved spectroscopy in Japanese, across a wide age range
- Author
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Masayuki Saito, Toshiyuki Homma, Sayuri Fuse, Takafumi Hamaoka, Yuko Kurosawa, Shiho Amagasa, Ryotaro Kime, Naoki Sakane, Tasuki Endo, Takeshi Yoneshiro, Shinsuke Nirengi, and Mami Matsushita
- Subjects
0301 basic medicine ,Adult ,Male ,medicine.medical_specialty ,animal structures ,Infrared Rays ,Biomedical Engineering ,Computed tomography ,Biology ,Biomaterials ,03 medical and health sciences ,Young Adult ,Adipose Tissue, Brown ,Asian People ,Japan ,Internal medicine ,Brown adipose tissue ,medicine ,Humans ,Visceral fat ,Aged ,Aged, 80 and over ,Spectroscopy, Near-Infrared ,medicine.diagnostic_test ,Anthropometry ,Near-infrared spectroscopy ,Middle Aged ,Atomic and Molecular Physics, and Optics ,Total hemoglobin ,Electronic, Optical and Magnetic Materials ,030104 developmental biology ,medicine.anatomical_structure ,Endocrinology ,Tissue optics ,Supraclavicular region ,Female ,BAT activity - Abstract
F18-fluorodeoxyglucose (FDG)–positron emission tomography (PET) along with computed tomography (CT) is a standard method for assessing brown adipose tissue (BAT) activity. We tested the usefulness of near-infrared time-resolved spectroscopy (NIRTRS) as a simple and noninvasive method for evaluating BAT density (BAT-d) by examining the effects of some factors known to influence BAT activity. The total hemoglobin concentration as a parameter of BAT-d was evaluated using NIRTRS in the supraclavicular region in 413 Japanese individuals. The associations were analyzed between BAT-d and sex, age, the percentages of body fat (%BF), visceral fat (VF), and the seasonal ambient temperature (AmT) fluctuations. Age was associated with decreased BAT-d (P
- Published
- 2018