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Your search keyword '"Wen Hsin Chang"' showing total 5 results
Start Over Author "Wen Hsin Chang" Journal journal of biomedical science
5 results on '"Wen Hsin Chang"'

1. Subject Index Vol. 10, 2003

Author

Mei-Sue Chen, Jen-Hwey Chiu, Hsing I. Chen, Wann-Cherng Perng, Jianning Wei, Chien-Hung Chen, Ya-Chen Liu, Małgorzata Szereda-Przestaszewska, Hong-Jen Lee, Sumio Sugano, Shu-Min Lin, Ann-Ping Tsou, Stephen C. Fowler, Chu-Wen Yang, Annelies Hauspie, Nada H. Khattar, Jen-Chine Wu, Wei-Kuang Liu, Richard B. Markham, David Camerini, Rong Chen, Christine Neuveut, Yi-Da Chung, Seng-Sheen Fan, Chien-Wen Hou, Chien-Huang Lin, Meng-Chun Hu, Carl Denef, Chin-Pyng Wu, Chien-Ying Liu, Marcin Rozalski, Ing-Cherng Guo, Yi-Ting Chen, Chen-Kung Chou, Y.S. Chan, Wei-Teing Chen, Luo-Hwa Miau, Jin-Tun Lin, Chain Fa Su, Chia-Hua Kuo, Laura De Marchis, Mei-Ling Chang, Chih-Ten Yu, Cezary Watala, Yu-Lun Liao, Eve Seuntjens, Vivian C. Yang, Di Sha, Wen-Hsin Huang, Horng-Chyuan Lin, Chun-Chung Lee, D.K.Y. Shum, Yu-Chi Chuang, Jung-Yaw Lin, Wan-An Lu, Jacek Golanski, Ben Berkhout, Cheng-Deng Kuo, Hsin-Yi Ho, Kerry Wu, Vincent J. Blanch, Wen-Chang Chang, Jang-Yen Wu, Chun-Hua Wang, Daniel Cupac, Kou-Gi Shyu, David Wang, Wen-Hsin Chang, Han-Pin Kuo, Ching-Hung Lin, Che-Yi Chao, Sharon Bargo, Chia-Chu Tsai, Jui-Fen Lin, K.K.L. Yung, Ru Ping Lee, Michael M.C. Lai, Beata Kopczyńska, June L. Traicoff, Wei-Ting Chao, Yutaka Suzuku, Charlotte S. Kaetzel, Kuan-Teh Jeang, Ying Jin, Kun-Ze Lee, Ying-Chih Chi, Robert M. Scoggins, Shankung Lin, Bao-Wei Wang, Shang Jyh Kao, Rodolfo E. Zamora, Britten L. Ginsburg, I-Jung Lu, Heng Wu, Ding-Shinn Chen, Bon Chu Chung, Hang Chang, Boguslawa Luzak, Yu-Ling Sung, Albert M. Wu, Wen-Chih Lee, C.H. Lai, Dennis J. Templeton, Yu-Chia Su, P.C. Joost Haasnoot, Jin-Yuan Su, Hugo Vankelecom, Daniel Fu-Chang Tsai, Fu-Chiu Yu, L.W. Chen, John T. Kung, Ling-Ling Chiou, Hsuan-Shu Lee, F.X. Zhang, Sarah J. Plummer, Guan-Tarn Huang, Pei-Ming Yang, Shih-Wei Chou, Horng-Chin Yan, Li-Chi Ku, Yun-Hen Liu, Samuel H.H. Chan, Ji-Chuu Hwang, Jin-Chuan Sheu, Ching-jang Huang, Shiow-Chwen Tsai, and Graham Casey

Subjects
Index (economics), Endocrinology, Diabetes and Metabolism, Biochemistry (medical), Clinical Biochemistry, Statistics, Pharmacology (medical), Subject (documents), Cell Biology, General Medicine, Molecular Biology, Mathematics
Published
2003
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2. Contents Vol. 10, 2003

Author

Jin-Chuan Sheu, Hong-Jen Lee, Ching-jang Huang, Chien-Hung Chen, Fu-Chiu Yu, Shiow-Chwen Tsai, Pei-Ming Yang, Li-Chi Ku, Chia-Hua Kuo, Graham Casey, Ji-Chuu Hwang, Ya-Chen Liu, Seng-Sheen Fan, Chien-Wen Hou, Rodolfo E. Zamora, Y.S. Chan, Sarah J. Plummer, Jen-Chine Wu, Chien-Ying Liu, Bon Chu Chung, Mei-Sue Chen, Chen-Kung Chou, Horng-Chyuan Lin, Guan-Tarn Huang, Hsing I. Chen, Wei-Teing Chen, Laura De Marchis, F.X. Zhang, Cezary Watala, Jung-Yaw Lin, Yi-Ting Chen, D.K.Y. Shum, Nada H. Khattar, Kerry Wu, Mei-Ling Chang, Charlotte S. Kaetzel, Che-Yi Chao, Ing-Cherng Guo, Chin-Pyng Wu, Vincent J. Blanch, Beata Kopczyńska, Ben Berkhout, Yu-Lun Liao, Jui-Fen Lin, Wen-Hsin Huang, Cheng-Deng Kuo, Daniel Cupac, K.K.L. Yung, David Wang, Han-Pin Kuo, Wei-Ting Chao, Yutaka Suzuku, Yu-Chia Su, Chun-Hua Wang, Kun-Ze Lee, Ying-Chih Chi, Yu-Chi Chuang, P.C. Joost Haasnoot, I-Jung Lu, Albert M. Wu, Ding-Shinn Chen, Dennis J. Templeton, Ching-Hung Lin, Wen-Chih Lee, Jin-Yuan Su, C.H. Lai, Hugo Vankelecom, Britten L. Ginsburg, Wen-Hsin Chang, Heng Wu, Bao-Wei Wang, Shang Jyh Kao, Wan-An Lu, Jin-Tun Lin, Daniel Fu-Chang Tsai, Wei-Kuang Liu, Hang Chang, Boguslawa Luzak, Chih-Ten Yu, Hsin-Yi Ho, Yu-Ling Sung, Shu-Min Lin, Sharon Bargo, Wen-Chang Chang, Annelies Hauspie, Michael M.C. Lai, L.W. Chen, Yi-Da Chung, John T. Kung, Ling-Ling Chiou, Hsuan-Shu Lee, Jianning Wei, Chu-Wen Yang, David Camerini, June L. Traicoff, Marcin Rozalski, Vivian C. Yang, Jacek Golanski, Di Sha, Małgorzata Szereda-Przestaszewska, Robert M. Scoggins, Shankung Lin, Ru Ping Lee, Rong Chen, Yun-Hen Liu, Meng-Chun Hu, Samuel H.H. Chan, Ann-Ping Tsou, Stephen C. Fowler, Richard B. Markham, Shih-Wei Chou, Carl Denef, Jen-Hwey Chiu, Kuan-Teh Jeang, Chien-Huang Lin, Ying Jin, Horng-Chin Yan, Chain Fa Su, Eve Seuntjens, Sumio Sugano, Chun-Chung Lee, Wann-Cherng Perng, Christine Neuveut, Kou-Gi Shyu, Chia-Chu Tsai, Jang-Yen Wu, and Luo-Hwa Miau

Subjects
Endocrinology, Diabetes and Metabolism, Biochemistry (medical), Clinical Biochemistry, Pharmacology (medical), Cell Biology, General Medicine, Molecular Biology
Published
2003
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3. Identification of differentially expressed genes in clear cell renal cell carcinoma by analysis of full-length enriched cDNA library

Author

Chyong-Ing Hsu, Sai-Wen Tang, Chung-Yei Lin, Jung-Yaw Lin, Wen-Hsin Chang, Yu-Chi Chen, Hsiao-Fen Chen, Yih-Ching Su, Ming-Kuen Lai, Sen-Wen Jane, Bo-Wen Zhan, Kao-Chung Wang, Yu-Wei Chao, Wei-Chou Lin, and Yen-Han Lai

Subjects
Sequence analysis, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Biology, Argininosuccinate Synthase, Renal cell carcinoma, medicine, Humans, Pharmacology (medical), Molecular Biology, Gene, Carcinoma, Renal Cell, Annexin A2, Gene Library, Kidney, cDNA library, Gene Expression Profiling, Biochemistry (medical), Cell Biology, General Medicine, medicine.disease, Molecular biology, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, Clear cell renal cell carcinoma, medicine.anatomical_structure, Clear cell
Abstract

Renal cell carcinoma (RCC) is the most common malignancy in adult kidney, and accounts for 3% of malignancies worldwide with increasing incidence. Clear cell RCC (ccRCC) is the major type in RCC. Resection by surgery is the main treatment because the response of ccRCC to traditional therapies is very poor. To identify the tumor-associated genes for better understanding the molecular mechanism of ccRCC, the full-length enriched cDNA libraries of ccRCC and normal kidney tissues were constructed by the oligo-capping method. Nucleotide sequences of the cDNA libraries of ccRCC and normal kidney tissues were sequenced. From the sequence analysis of 19,425 and 12,400 clones of ccRCC and normal kidney tissues, 4356 and 3055 genes were identified, respectively. By comparing the gene-expression patterns of ccRCC and normal tissues, the up- or down-regulated genes were identified. Among these identified genes, the differential expression of annexin A2 and argininosuccinate synthetase genes were further confirmed by quantitative real-time PCR and Western blot analysis.

Published
2006

4. Large-scale sequencing analysis of the full-length cDNA library of human hepatocellular carcinoma

Author

Chia-Chu Tsai, Yi-Da Chung, Hong-Jen Lee, Wen-Hsin Chang, Yutaka Suzuku, Sumio Sugano, and Jung-Yaw Lin

Subjects
Male, Carcinoma, Hepatocellular, Endocrinology, Diabetes and Metabolism, Gene Expression Profiling, Biochemistry (medical), Clinical Biochemistry, Liver Neoplasms, Cell Biology, General Medicine, Sequence Analysis, DNA, Humans, Pharmacology (medical), Molecular Biology, Aged, Gene Library, Oligonucleotide Array Sequence Analysis
Abstract

Hepatocellular carcinoma (HCC) is one of the human cancers clearly linked to viral infections. Although the major risk factors for HCC development have been elucidated, the hepatocellular carcinogenesis pathway resulting in malignant transformation of liver cells remains to be clarified. Recently, some results of microarray and comparative genomic hybridization analysis have been provided as comprehensive studies of genomic instability in HCC, including mutation, deletion and DNA copy losses. In this work, the full-length cDNA library has been constructed and sequenced, and the sequencing results have been further clustered and analyzed. The results show that 1,342 genes have been found, and about 300 of these genes may be important in e.g. cell proliferation, DNA repair and apoptosis. After further analysis of DNA sequences, the deletion genotypes of at least 24 genes have been found. However, the functional changes of these deletion mutants and their significance in hepatocellular carcinogenesis remain to be clarified. This research may be one of the best to obtain the candidate genes for hepatocellular carcinogenesis.

Published
2003

5. Identification of differentially expressed genes in clear cell renal cell carcinoma by analysis of full-length enriched cDNA library.

Author

Sai-Wen Tang, Wen-Hsin Chang, Yu-Wei Chao, Chung-Yei Lin, Hsiao-Fen Chen, Yen-Han Lai, Bo-Wen Zhan, Yih-Ching Su, Sen-Wen Jane, Yu-Chi Chen, Chyong-Ing Hsu, Wei-Chou Lin, Kao-Chung Wang, Ming-Kuen Lai, and Jung-Yaw Lin

Subjects
*RENAL cell carcinoma, *ANTISENSE DNA, *ANNEXINS, *KIDNEY tumors, *TUMORS
Abstract

Renal cell carcinoma (RCC) is the most common malignancy in adult kidney, and accounts for 3% of malignancies worldwide with increasing incidence. Clear cell RCC (ccRCC) is the major type in RCC. Resection by surgery is the main treatment because the response of ccRCC to traditional therapies is very poor. To identify the tumor-associated genes for better understanding the molecular mechanism of ccRCC, the full-length enriched cDNA libraries of ccRCC and normal kidney tissues were constructed by the oligo-capping method. Nucleotide sequences of the cDNA libraries of ccRCC and normal kidney tissues were sequenced. From the sequence analysis of 19,425 and 12,400 clones of ccRCC and normal kidney tissues, 4356 and 3055 genes were identified, respectively. By comparing the gene-expression patterns of ccRCC and normal tissues, the up- or down-regulated genes were identified. Among these identified genes, the differential expression of annexin A2 and argininosuccinate synthetase genes were further confirmed by quantitative real-time PCR and Western blot analysis. [ABSTRACT FROM AUTHOR]

Published
2006
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