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Your search keyword '"Osamah Alduhaish"' showing total 2 results
Start Over Author "Osamah Alduhaish" Journal journal of chemistry
2 results on '"Osamah Alduhaish"'

1. Synthesis of 1,2-Dihydro-Substituted Aniline Analogues Involving N-Phenyl-3-aza-Cope Rearrangement Using a Metal-Free Catalytic Approach

Author

Osamah Alduhaish, Ravi Varala, Syed Farooq Adil, Mujeeb Khan, Mohammed Rafiq H. Siddiqui, Abdulrhman AlWarthan, and M. Mujahid Alam

Subjects
Chemistry, QD1-999
Abstract

An efficient metal-free domino reaction leading to structural/electronically divergent 1,2-dihydropyridines from easily accessible propargyl vinyl anilines via N-phenyl 3-aza-Cope sigmatropic rearrangement is reported with good to excellent yields using 1,2-dichlorobenzene as solvent under thermal conditions. Spirocyclic substitution is also tolerated under the present optimized conditions.

Published
2020
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2. Synthesis of 1,2-Dihydro-Substituted Aniline Analogues Involving N-Phenyl-3-aza-Cope Rearrangement Using a Metal-Free Catalytic Approach

Author

Mohammed Rafiq H. Siddiqui, Syed Farooq Adil, Ravi Varala, Mujeeb Khan, Osamah Alduhaish, Abdulrhman Al-Warthan, and Mohammed Mujahid Alam

Subjects
Article Subject, 010405 organic chemistry, General Chemistry, Sigmatropic reaction, 010402 general chemistry, 01 natural sciences, Medicinal chemistry, 0104 chemical sciences, Catalysis, Solvent, Chemistry, chemistry.chemical_compound, Aniline, chemistry, Cascade reaction, Propargyl, Aza-Cope rearrangement, QD1-999
Abstract

An efficient metal-free domino reaction leading to structural/electronically divergent 1,2-dihydropyridines from easily accessible propargyl vinyl anilines via N-phenyl 3-aza-Cope sigmatropic rearrangement is reported with good to excellent yields using 1,2-dichlorobenzene as solvent under thermal conditions. Spirocyclic substitution is also tolerated under the present optimized conditions.

Published
2020

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