Search

Your search keyword '"T.M. Jefferies"' showing total 2 results
Start Over Author "T.M. Jefferies" Journal journal of chromatography b: biomedical sciences and applications
2 results on '"T.M. Jefferies"'

1. Surfactant ion-pair high-performance liquid chromatography of tryptophan and some of its metabolites in biological fluids

Author

E. Tomlinson, P. H. Redfern, C.M. Riley, and T.M. Jefferies

Subjects
Male, Saliva, Chromatography, Sodium, Tryptophan, Biological Availability, chemistry.chemical_element, General Chemistry, Urine, Ion pairs, High-performance liquid chromatography, chemistry.chemical_compound, chemistry, Pulmonary surfactant, Biochemistry, Methods, Humans, Biotransformation, Chromatography, High Pressure Liquid, Kynurenine
Abstract

A rapid, sensitive assay for tryptophan and some of its metabolites in urine, plasma and saliva has been developed using sodium dodecylsulphate as a pairing ion in a surfactant ion-pair high-performance liquid chromatography technique. The method is highly selective for tryptophan which is separated from its main indoleamine metabolites, 5-hydroxytryptophan, 5-hydroxytryptamine and 5-hydroxyindoleacetic acid, and from kynurenine. The usefulness of the assay has been demonstrated in plasma level and urinary excretion studies of orally administered tryptophan.

Published
1979
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results