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1. Screening of small molecule inhibitors against RhoA protein from Alisma using an online detection system

Author

Chenjia Yan, Hong Wang, and Shizhong Chen

Subjects
Biological Products, Organic Chemistry, Alisma, General Medicine, rhoA GTP-Binding Protein, Biochemistry, Online Systems, Analytical Chemistry
Abstract

Targeted high-throughput screening of inhibitors from natural products is an effective approach in the treatment of cancer progression. RhoA protein is essential for many signaling pathways. It is closely related to the occurrence and development of tumor. So far, there are only a few reports on the screening of small molecule inhibitors of RhoA protein from natural products. In this study, an online UHPLC-PDA-MS

Published
2022

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