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Start Over Author "Ly, San" Journal journal of clinical investigation
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1. AMPK dysregulation promotes diabetes-related reduction of superoxide and mitochondrial function

Author

Dugan, Laura L., You, Young-Hyun, Ali, Sameh S., Diamond-Stanic, Maggie, Miyamoto, Satoshi, DeCleves, Anne-Emilie, Andreyev, Aleksander, Quach, Tammy, Ly, San, Shekhtman, Grigory, Nguyen, William, Chepetan, Andre, Le, Thuy P., Wang, Lin, Xu, Ming, Paik, Kacie P., Fogo, Agnes, Viollet, Benoit, Murphy, Anne, Brosius, Frank, Naviaux, Robert K., and Sharma, Kumar

Subjects
Superoxide -- Physiological aspects -- Genetic aspects -- Research, Type 1 diabetes -- Diagnosis -- Care and treatment -- Research, Cyclic adenylic acid -- Physiological aspects -- Genetic aspects -- Research, Protein kinases -- Physiological aspects -- Genetic aspects -- Research, Health care industry
Abstract

Diabetic microvascular complications have been considered to be mediated by a glucose-driven increase in mitochondrial superoxide anion production. Here, we report that superoxide production was reduced in the kidneys of [...]

Published
2013

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