1. Imaging in Primary Sjögren’s Syndrome
- Author
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Hendrika Bootsma, Bert van der Vegt, Andor W. J. M. Glaudemans, Frans G. M. Kroese, Arjan Vissink, Esther Mossel, and Martha S van Ginkel
- Subjects
musculoskeletal diseases ,medicine.medical_specialty ,positron emission tomography ,primary Sjögren’s syndrome ,MAGNETIC-RESONANCE SIALOGRAPHY ,lcsh:Medicine ,salivary gland ,Signs and symptoms ,primary Sjogren's syndrome ,Review ,salivary gland scintigraphy ,Lacrimal gland ,03 medical and health sciences ,POSITRON-EMISSION-TOMOGRAPHY ,sialendoscopy ,0302 clinical medicine ,stomatognathic system ,MALIGNANT-LYMPHOMA ,medicine ,magnetic resonance imaging ,CLASSIFICATION CRITERIA ,NON-HODGKINS-LYMPHOMA ,sialography ,salivary gland ultrasonography ,030203 arthritis & rheumatology ,Lymphocytic infiltration ,PAROTID-GLAND ,medicine.diagnostic_test ,Salivary gland ,business.industry ,lcsh:R ,FOCUS SCORE ,imaging ,Magnetic resonance imaging ,General Medicine ,Dermatology ,eye diseases ,LACRIMAL GLAND ,3. Good health ,Parotid gland ,PROGNOSTIC VALUE ,stomatognathic diseases ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,SALIVARY-GLAND ULTRASONOGRAPHY ,Sialography ,Sjogren s ,business - Abstract
Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease characterized by dysfunction and lymphocytic infiltration of the salivary and lacrimal glands. Besides the characteristic sicca complaints, pSS patients can present a spectrum of signs and symptoms, which challenges the diagnostic process. Various imaging techniques can be used to assist in the diagnostic work-up and follow-up of pSS patients. Developments in imaging techniques provide new opportunities and perspectives. In this descriptive review, we discuss imaging techniques that are used in pSS with a focus on the salivary glands. The emphasis is on the contribution of these techniques to the diagnosis of pSS, their potential in assessing disease activity and disease progression in pSS, and their contribution to diagnosing and staging of pSS-associated lymphomas. Imaging findings of the salivary glands will be linked to histopathological changes in the salivary glands of pSS patients.
- Published
- 2020
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