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Your search keyword '"calcium silicate cements"' showing total 2 results
Start Over Descriptor "calcium silicate cements" Journal journal of clinical medicine
2 results on '"calcium silicate cements"'

1. Cytocompatibility and Bioactive Properties of Hydraulic Calcium Silicate-Based Cements (HCSCs) on Stem Cells from Human Exfoliated Deciduous Teeth (SHEDs): A Systematic Review of In Vitro Studies

Author

Julia Guerrero-Gironés, Francisco Javier Rodríguez-Lozano, Gianrico Spagnuolo, Carmen Llena, Sandro Rengo, José Luis Sanz, Leopoldo Forner, María Melo, Sanz, José Lui, Forner, Leopoldo, Llena, Carmen, Guerrero-Gironés, Julia, Melo, María, Rengo, Sandro, Spagnuolo, Gianrico, and Rodríguez-Lozano, Francisco Javier

Subjects
lcsh:Medicine, Review, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, calcium silicate cements, Deciduous teeth, Medicine, dental stem cells, Viability assay, Proroot mta, cell viability, 030304 developmental biology, 0303 health sciences, business.industry, lcsh:R, In vitro toxicology, 030206 dentistry, General Medicine, In vitro, medicine.anatomical_structure, chemistry, bioceramic, bioactivity, Calcium silicate, Cancer research, Stem cell, Nodule formation, business
Abstract

The implementation of hydraulic calcium silicate-based endodontic cements (HCSCs) in biologically based endodontic procedures for the primary dentition has been recently investigated, focusing on the biological response of stem cells from human exfoliated deciduous teeth (SHEDs) towards them. The present systematic review aimed to present a qualitative synthesis of the available literature consisting of in vitro assays, which assessed the cytocompatibility and bioactive properties of HCSCs in direct contact with SHEDs. Following the PRISMA statement, an electronic database search was carried out in Medline, Scopus, Embase, Web of Science, and SciELO on March 31st and updated on November 16th, 2020. In vitro studies evaluating the biological response of SHEDs to the treatment with HCSCs were eligible. Within the term biological response, assays assessing the cytocompatibility (i.e., cell viability, migration, proliferation), cell plasticity or differentiation (i.e., osteo/odontogenic marker expression), and bioactivity or biomineralization (i.e., mineralized nodule formation) were included. A total of seven studies were included after the selection process. The study sample comprised an extensive range of cell viability, migration, proliferation, adhesion, and bioactivity assays regarding the biological response of SHEDs towards five different commercially available HCSCs (MTA, ProRoot MTA, Biodentine, iRoot BP Plus, and Theracal LC). Biodentine, MTA, and iRoot BP Plus showed significant positive results in cytocompatibility and bioactivity assays when cultured with SHEDs. The results from in vitro assays assessing the cytocompatibility and bioactivity of the HCSCs MTA, Biodentine, and iRoot BP Plus towards SHEDs support their use in vital pulp treatment for the primary dentition.

Published
2020

2. Cytocompatibility and Bioactive Properties of Hydraulic Calcium Silicate-Based Cements (HCSCs) on Stem Cells from Human Exfoliated Deciduous Teeth (SHEDs): A Systematic Review of In Vitro Studies.

Author

Sanz, José Luis, Forner, Leopoldo, Llena, Carmen, Guerrero-Gironés, Julia, Melo, María, Rengo, Sandro, Spagnuolo, Gianrico, and Rodríguez-Lozano, Francisco Javier

Subjects
*HUMAN stem cells, *DECIDUOUS teeth, *SILICATE cements (Dentistry), *CALCIUM, *CEMENT, *CELL survival, *CYTOCOMPATIBILITY
Abstract

The implementation of hydraulic calcium silicate-based endodontic cements (HCSCs) in biologically based endodontic procedures for the primary dentition has been recently investigated, focusing on the biological response of stem cells from human exfoliated deciduous teeth (SHEDs) towards them. The present systematic review aimed to present a qualitative synthesis of the available literature consisting of in vitro assays, which assessed the cytocompatibility and bioactive properties of HCSCs in direct contact with SHEDs. Following the PRISMA statement, an electronic database search was carried out in Medline, Scopus, Embase, Web of Science, and SciELO on March 31st and updated on November 16th, 2020. In vitro studies evaluating the biological response of SHEDs to the treatment with HCSCs were eligible. Within the term biological response, assays assessing the cytocompatibility (i.e., cell viability, migration, proliferation), cell plasticity or differentiation (i.e., osteo/odontogenic marker expression), and bioactivity or biomineralization (i.e., mineralized nodule formation) were included. A total of seven studies were included after the selection process. The study sample comprised an extensive range of cell viability, migration, proliferation, adhesion, and bioactivity assays regarding the biological response of SHEDs towards five different commercially available HCSCs (MTA, ProRoot MTA, Biodentine, iRoot BP Plus, and Theracal LC). Biodentine, MTA, and iRoot BP Plus showed significant positive results in cytocompatibility and bioactivity assays when cultured with SHEDs. The results from in vitro assays assessing the cytocompatibility and bioactivity of the HCSCs MTA, Biodentine, and iRoot BP Plus towards SHEDs support their use in vital pulp treatment for the primary dentition. [ABSTRACT FROM AUTHOR]

Published
2020
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