1. Buruli ulcer disease in travelers and differentiation of Mycobacterium ulcerans strains from northern Australia
- Author
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Maria Globan, Paul D R Johnson, Niladri Ghosh, P. G. P. Charles, Janet A. M. Fyfe, Caroline J. Lavender, Benjamin M. Clark, Marianne Martinello, and Grant A. Jenkin
- Subjects
Microbiology (medical) ,Buruli ulcer ,Adult ,Male ,Genotype ,Epidemiology ,Molecular typing ,medicine ,Cluster Analysis ,Humans ,Typing ,Buruli Ulcer ,Phylogeny ,Aged ,Molecular Epidemiology ,Travel ,Polymorphism, Genetic ,Molecular epidemiology ,biology ,Mycobacterium ulcerans ,Australia ,Buruli Ulcer Disease ,Middle Aged ,biology.organism_classification ,medicine.disease ,Virology ,Molecular Typing ,Northern australia ,Female ,human activities - Abstract
Buruli ulcer (BU) is a necrotizing infection of skin and soft tissue caused by Mycobacterium ulcerans . In Australia, most cases of BU are linked to temperate, coastal Victoria and tropical, northern Queensland, and strains from these regions are distinguishable by variable-number tandem repeat (VNTR) typing. We present an epidemiological investigation of five patients found to have been infected during interstate travel and describe two nucleotide polymorphisms that differentiate M. ulcerans strains from northern Australia.
- Published
- 2012