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Start Over Descriptor "Chickenpox cerebrospinal fluid" Journal journal of clinical microbiology

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1. Detection of varicella-zoster virus DNA by polymerase chain reaction in the cerebrospinal fluid of patients suffering from neurological complications associated with chicken pox or herpes zoster.

Author

Puchhammer-Stöckl E, Popow-Kraupp T, Heinz FX, Mandl CW, and Kunz C

Subjects
Chickenpox cerebrospinal fluid, Chickenpox complications, Child, Encephalitis cerebrospinal fluid, Encephalitis etiology, Encephalitis microbiology, Herpes Zoster cerebrospinal fluid, Herpes Zoster complications, Humans, Meningitis, Viral cerebrospinal fluid, Meningitis, Viral etiology, Meningitis, Viral microbiology, Polymerase Chain Reaction, Chickenpox microbiology, DNA, Viral cerebrospinal fluid, Herpes Zoster microbiology, Herpesvirus 3, Human isolation & purification
Abstract

The polymerase chain reaction (PCR) was used to detect varicella-zoster virus (VZV) DNA in the cerebrospinal fluid of patients with VZV infection associated with neurological symptoms. Positive results were obtained in three of five children with post-chicken pox cerebellitis and in seven of seven herpes zoster patients with neurological symptoms. The PCR thus provides a useful tool for the early diagnosis of VZV-associated neurological disease.

Published
1991
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