1. Case Report of Calciphylaxis Secondary to Calcium and Vitamin D3 Supplementation
- Author
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Annette Murphy, Mary E. Laing, Susan M. O’Gorman, and Eoin R. Storan
- Subjects
Vitamin ,medicine.medical_specialty ,Sodium ,030232 urology & nephrology ,chemistry.chemical_element ,Dermatology ,030204 cardiovascular system & hematology ,Calcium ,Gastroenterology ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Internal medicine ,medicine ,Vitamin D and neurology ,Calciphylaxis ,Kidney ,medicine.diagnostic_test ,business.industry ,medicine.disease ,Response to treatment ,Endocrinology ,medicine.anatomical_structure ,chemistry ,Skin biopsy ,Surgery ,business - Abstract
Background: Calciphylaxis is a rare disorder that is very unusual outside the setting of end-stage kidney disease. Case Summary: A 64-year-old woman with normal renal function presented with painful leg ulcers. She had previously received 300 000 IU of vitamin D3 followed by daily calcium and vitamin D3 supplementation. A skin biopsy was consistent with calciphylaxis, and she was treated with sodium thiosulphate infusions and wound debridement. Conclusion: Calcium and vitamin D3 supplements are widely prescribed. We report a case of calciphylaxis triggered by calcium and vitamin D3 supplementation in a patient with none of the typical risk factors. Our patient had an excellent response to treatment with sodium thiosulphate.
- Published
- 2016
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