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Purpose/objectives: The objectives of this study were to assess the influence of learner‐ and education‐related factors on standardized in‐service examination performance and determine whether in‐service examination scores predict residency outcomes. Methods: American Academy of Periodontology (AAP) In‐service Examination (AIE) scores from 10 periodontics residency classes at a single center were recorded and compared against a panel of learner‐ and education‐related variables using multiple linear regression models. Defined residency outcome measures were analyzed against AIE scores using binomial logistic regression. Results: No evaluated learner‐ or education‐related variable was a statistically significant predictor of AIE score in this study sample. Likewise, AIE score was not a statistically significant predictor of any assessed residency outcome. Conclusions: The AAP has performed a tremendous service to periodontics residents and programs by marshaling the leadership and expertise necessary to offer a professionally constructed assessment instrument. However, in the current study, no relationship could be identified between AIE score and any outcome, including first‐attempt board certification. The AAP In‐service Committee appears well situated to provide additional leadership focusing on exam implementation, which may enhance AIE value in competency decision making. [ABSTRACT FROM AUTHOR]