According to The National Kidney Foundation, 20 million Americans have Chronic Kidney Disease (CKD). Given the prevalence of conditions such as diabetes and hypertension, it is estimated that an additional 20 million people are at an increased risk for developing CKD. Research suggests chronic renal failure can give rise to a wide spectrum of oral manifestations affecting the hard or soft tissues of the mouth. Likewise, periodontitis may contribute to the burden of systemic inflammation in these patients. Unfortunately, CKD patients and their health care providers are often unaware of the oral complications of the disease as well as the multiple systems that can be affected. The complexity of care for patients with CKD reinforces the need for collaboration between healthcare providers. The purpose of this study was to raise oral health awareness by providing educational seminars to healthcare providers, specifically nephrology nurses. By doing so they should be able to recognize early oral manifestations, provide basic patient education, and when necessary, make referrals to address these concerns. Educational seminars entitled Oral Health and Chronic Kidney Disease were delivered by calibrated dental hygiene educators to renal nurses in three different regions in the United States. The nurse participants (n=106) were given randomly assigned pre- and post-tests, assessing their knowledge of oral health (OH) and its relation to CKD. These tests consisted of six multiple choice and four true/false questions. Pre-tests revealed that nurses had little knowledge of oral health and its relation to CKD. Regardless of questionnaire order, a significant increase of knowledge was observed for both groups (p-value ≤ 0.015), increasing from 61% to 76% on average. Incorporating interdisciplinary education, such as the educational seminar, benefits nurses’ knowledge and can potentially lead to greater quality of life outcomes and improved overall health in patients with Chronic Kidney Disease. [ABSTRACT FROM AUTHOR]